| Cat.No. | Name | Information |
|---|---|---|
| M1641 | Quizartinib (AC220) | Quizartinib (AC220) is a uniquely potent and selective FLT3 inhibitor. |
| M7527 | Gilteritinib | Gilteritinib is a potent FLT3/AXL inhibitor with IC50 of 0.29 nM/0.73 nM, respectively. |
| M57206 | 4SC-203 | 4SC-203 is a potent multikinase inhibitor with potential antineoplastic activity. |
| M57205 | AKN-028 | AKN-028, a novel tyrosine kinase (TK) inhibitor, is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. |
| M57204 | FLT3-IN-3 | FLT3-IN-3 is a potent FLT3 inhibitor with IC50s of 13 and 8 nM for FLT3 WT and FLT3 D835Y, respectively. |
| M57203 | MAX-40279 | MAX-40279 is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. |
| M57202 | FLT3-IN-10 | FLT3-IN-10 is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). |
| M57201 | CHMFL-FLT3-122 | CHMFL-FLT3-122 is a potent, selective and orally active FLT3 kinase with an IC50 of 40 nM. |
| M57200 | MAX-40279 hemiadipate | MAX-40279 hemiadipate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. |
| M57199 | MAX-40279 hemifumarate | MAX-40279 hemifumarate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. |
| M57198 | MAX-40279 hydrochloride | MAX-40279 hydrochloride is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. |
| M43515 | FLT3-IN-19 | FLT3-IN-19 is a potent and selective FLT3 inhibitor with IC50 of 0.213 nM. |
| M43514 | LT-540-717 | LT-540-717 is a potent FLT3 inhibitor (IC50=0.62 nM) with antiproliferative activity. |
| M43513 | GTP-14564 | GTP-14564 is a tyrosine kinase inhibitor targeting to internal tandem duplication (ITD) and FLT3. |
| M43512 | HDAC-IN-63 | HDAC-IN-63 is a dual FLT3/HDAC inhibitor (IC50: 0.844 and 30.0 nM for FLT3 and HDAC1 respectively). |
| M43511 | FLT3-IN-20 | FLT3-IN-20 is a potent FLT3 inhibitor with IC50 values of 1 and 4 nM for FLT3-D835Y and FLT3-ITD, respectively. |
| M40752 | Quizartinib hydrochloride | Quizartinib hydrochloride is a FLT3 inhibitor with IC50 values of 1.1 nM for Flt3-ITD and 4.2 nM for Flt3-WT, and is 10-fold more selective for Flt3 than for KIT, PDGFRA, PDGFRB, RET, and CSF-1R. It can be used in studies related to acute myeloid leukemia (AML). |
| M31079 | BPR1J-097 Hydrochloride | BPR1J-097 Hydrochloride is a novel and potent FLT3 inhibitor with an IC50 of 11 nM. |
| M30770 | TTT 3002 | TTT 3002 is a potent and orally active FLT3 inhibitor. TTT 3002 potently inhibits FLT3 phosphorylation by activating mutations at residue D835, with an IC50 of 0.2 nM. TTT 3002 can be used for AML (acute myeloid leukemia) research. |
| M30706 | JI6 | JI6 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively. JI6 also inhibits JAK3 and c-Kit, with IC50s of ∼250 and ∼500 nM, respectively. JI6 can be used for the research of acute myeloid leukemia. |
| M29644 | BPR1K871 | BPR1K871 is a potent and selective dual FLT3/AURKA inhibitor with IC50s of 19 nM and 22 nM for FLT3 and AURKA, respectively, acts as a preclinical development candidate for anti-cancer therapy. |
| M29490 | FLT3-IN-4 | FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia. |
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