About 15 results found for searched term "FLT3" (0.058 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9985 | Recombinant Human FLT3 Ligand Protein (HEK293) | Cytokines and Growth Factors |
| FLT3LG | ||
| FLT3-ligand (HEK293) is a growth factor that regulates the proliferation of early hematopoietic cells. FLT 3-ligand binds to cells expressing FLT 3, the tyrosine kinase receptor. | ||
| M10181 | STK321130 | FLT3 |
| FLT3-IN-2 | ||
| STK321130, also known as FLT3-IN-2, is potent FLT3 inhibitor with IC50 of <1 μM. | ||
| M20679 | SKLB4771 (FLT3-IN-1) | FLT3 |
| SKLB4771 is a potent and selective inhibitor of human receptor-type tyrosine-protein kinase FLT3 with IC50 of 10 nM. | ||
| M20702 | Alovudine | Reverse Transcriptase |
| CL 184824, FddThd, FLT, MIV-310 | ||
| 3'-Fluoro-3'-deoxythymidine (Alovudine) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer. | ||
| M22399 | FLT3 Inhibitor III | Others |
| FLT3 Inhibitor III | ||
| M29479 | FLT3/ITD-IN-4 | FLT3 |
| FLT3/ITD-IN-4 (Compound 16) is a selective FMS-like tyrosine kinase 3 internal tandem duplications (FLT3-ITD) inhibitor with an IC50 of 2.3 nM. FLT3/ITD-IN-4 can be used for acute myeloid leukemia research. | ||
| M29490 | FLT3-IN-4 | FLT3 |
| FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia. | ||
| M43511 | FLT3-IN-20 | FLT3 |
| FLT3-IN-20 is a potent FLT3 inhibitor with IC50 values of 1 and 4 nM for FLT3-D835Y and FLT3-ITD, respectively. | ||
| M43515 | FLT3-IN-19 | FLT3 |
| FLT3-IN-19 is a potent and selective FLT3 inhibitor with IC50 of 0.213 nM. | ||
| M49581 | JAK2/FLT3-IN-1 | JAK |
| JAK2/FLT3-IN-1 is a potent and orally active dual JAK2/FLT3 inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. | ||
| M49651 | JAK2/FLT3-IN-1 TFA | JAK |
| JAK2/FLT3-IN-1 (TFA) is a potent and orally active dual JAK2/FLT3 inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. | ||
| M55299 | Recombinant Human FLT3L (HEK293, C-6His) | Cytokines and Growth Factors |
| Fms-like Tyrosine Kinase 3 Ligand | ||
| Fms-like Tyrosine Kinase 3 Ligand (FLT3L) is a hematopoietic four helical bundle cytokine. Flt‑3 Ligand is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts. | ||
| M57204 | FLT3-IN-3 | FLT3 |
| FLT3-IN-3 is a potent FLT3 inhibitor with IC50s of 13 and 8 nM for FLT3 WT and FLT3 D835Y, respectively. | ||
| M57202 | FLT3-IN-10 | FLT3 |
| FLT3-IN-10 is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). | ||
| M57201 | CHMFL-FLT3-122 | FLT3 |
| CHMFL-FLT3-122 is a potent, selective and orally active FLT3 kinase with an IC50 of 40 nM. | ||
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