All AbMole products are for research use only, cannot be used for human consumption.
JAK2/FLT3-IN-1 (TFA) is a potent and orally active dual JAK2/FLT3 inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively.
| Molecular Weight | 581.61 |
| Formula | C27H35F4N7O3 |
| CAS Number | 2928093-29-0 |
| Form | Solid |
| Solubility (25°C) | Water 30 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
| Related JAK Products |
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| ZT55
ZT55 is an orally active and highly-selective JAK2 inhibitor with an IC50 value of 0.031 μM. |
| ZM39923
ZM39923 is a JAK3 inhibitor, with a pIC50 of 7.1; ZM39923 also potently inhibits tissue transglutaminase (TGM2) with an IC50 of 10 nM. |
| Upadacitinib tartrate tetrahydrate
Upadacitinib (ABT-494) tartrate tetrahydrate is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). |
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