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FLT3/ITD-IN-4 

Cat. No. M29479

All AbMole products are for research use only, cannot be used for human consumption.

FLT3/ITD-IN-4  Structure

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Quality Control & Documentation
Biological Activity

FLT3/ITD-IN-4 (Compound 16) is a selective FMS-like tyrosine kinase 3 internal tandem duplications (FLT3-ITD) inhibitor with an IC50 of 2.3 nM. FLT3/ITD-IN-4 can be used for acute myeloid leukemia research.

Chemical Information
Molecular Weight 458.47
Formula C25H22N4O5
CAS Number 2278278-04-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Kaosheng Lv, et al. Blood. Depalmitoylation rewires FLT3-ITD signaling and exacerbates leukemia progression

[2] Vanessa E Kennedy, et al. Front Oncol. FLT3 Mutations in Acute Myeloid Leukemia: Key Concepts and Emerging Controversies

[3] Naval Daver, et al. Leukemia. Targeting FLT3 mutations in AML: review of current knowledge and evidence

[4] Mei Wu, et al. J Hematol Oncol. FLT3 inhibitors in acute myeloid leukemia

[5] Francisco Alejandro Lagunas-Rangel, et al. Med Oncol. FLT3-ITD and its current role in acute myeloid leukaemia

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  Catalog
Abmole Inhibitor Catalog




Keywords: FLT3/ITD-IN-4  supplier, FLT3, inhibitors, activators

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