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Jaceosidin

Cat. No. M4637

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Jaceosidin Structure
Size Price Availability Quantity
1mg USD 55  USD55 In stock
5mg USD 120  USD120 In stock
10mg USD 190  USD190 In stock
20mg USD 290  USD290 In stock
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Quality Control & Documentation
Biological Activity

Jaceosidin is a flavonoid obtained from Artemisia vestita, which can activate Bax, down-regulate the expression of McL-1 and C-flip, and induce apoptosis of cancer cells. Jaceosidin has anti-cancer and anti-inflammatory effects, which can reduce the level of inflammatory factors, activate NF-κB, and inhibit the expression of COX-2.

Chemical Information
Molecular Weight 330.29
Formula C17H14O7
CAS Number 18085-97-7
Solubility (25°C) DMSO ≥ 36 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yuzhou Liu, et al. Protection against Doxorubicin-Related Cardiotoxicity by Jaceosidin Involves the Sirt1 Signaling Pathway

[2] Eunkyo Park, et al. Jaceosidin Ameliorates Insulin Resistance and Kidney Dysfunction by Enhancing Insulin Receptor Signaling and the Antioxidant Defense System in Type 2 Diabetic Mice

[3] Hyemi Lee, et al. Seomae mugwort and jaceosidin attenuate osteoarthritic cartilage damage by blocking IκB degradation in mice

[4] Bushra Nageen, et al. Jaceosidin: A Natural Flavone with Versatile Pharmacological and Biological Activities

[5] Wen-Rong Fu, et al. Bidirectional Regulatory Mechanisms of Jaceosidin on Mitochondria Function: Protective Effects of the Permeability Transition and Damage of Membrane Functions

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Keywords: Jaceosidin supplier, Bcl-2, inhibitors, activators

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