About 30 results found for searched term "mP6" (0.032 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1865 | Bevirimat | HIV Protease |
| BVM, MPC-4326, PA-457 | ||
| Bevirimat (BVM), also known as PA-457 or MPC-4326, is a novel Human Immunodeficiency Virus type 1 (HIV-1) maturation inhibitor. | ||
| M1918 | Amuvatinib | VEGFR/PDGFR |
| MP470; HPK 56 | ||
| Amuvatinib (MP470) is a novel receptor tyrosine kinase inhibitor that targets c-KIT and PDGFRα. | ||
| M2521 | Cinoxacin | Antibiotic |
| Compound 64716 | ||
| Cinoxacin is a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. | ||
| M2581 | Ampalex | GluR |
| Ampakine CX516, BDP 12 | ||
| Ampalex is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator which can be used for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). | ||
| M2846 | Mevastatin | Others |
| Compactin; ML236B | ||
| Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself. | ||
| M2868 | MPI-0479605 | Kinesin |
| MPI-0479605 is an ATP competitive and selective inhibitor of mitotic kinase Mps1 with IC50 of 1.8 nM, >40-fold selectivity over other kinases. | ||
| M2922 | Pentamidine dihydrochloride | Parasite |
| MP601205 dihydrochloride | ||
| Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein. | ||
| M3262 | Methotrexate metabolite | Antifolate |
| DAMPA; NSC 131463 | ||
| Methotrexate metabolite is a dihydrofolate reductase potent inhibitor with an IC50 of 1 nM. | ||
| M3643 | TMP269 | HDAC |
| TMP269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.In addition, TMP269 significantly promotes reprogramming. | ||
| M3737 | Pyridone 6 | JAK |
| Merck-5, CMP 6, JAK Inhibitor I | ||
| Pyridone 6 is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK1 (IC50 = 15 nM for murine JAK1), JAK2 (IC50 = 1 nM), JAK3 (Ki = 5 nM), and Tyk 2 (IC50 = 1 nM) (Janus protein tyrosine kinases). | ||
| M5366 | 4-Aminoantipyrine | COX |
| Ampyrone, NSC 60242 | ||
| 4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. | ||
| M5605 | Efavirenz | Reverse Transcriptase |
| Sustiva, Stocrin, DMP-266 | ||
| Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture. | ||
| M6285 | Glutaminase C-IN-1 | Glutaminase |
| Compound 968 | ||
| Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts. | ||
| M9049 | MPTP HCl | Dopamine Receptor |
| MPTP hydrochloride; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Hydrochloride | ||
| MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. | ||
| M9720 | Aranidipine | Calcium Channel |
| MPC1304; CCRIS-6724 | ||
| Aranidipine (MPC1304) is a calcium channel blocker which may positively affect ambulatory blood pressure. *This compound is unstable in solutions, freshly prepared is recommended. | ||
| M10749 | Verubulin | Microtubule |
| MPC 6827 | ||
| Verubulin (MPC-6827) is a highly effective, broad-spectrum microtubule blocker with in vivo and in vitro cytotoxic activity, promising as a potential drug candidate for a wide range of cancers. | ||
| M13668 | TMPyP4 tosylate | DNA/RNA Synthesis |
| TMP 1363 | ||
| TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand, which inhibits the interaction between G-quadruplexes and IGF-1. TMPyP4 tosylate (TMP 1363) is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines. | ||
| M14524 | Tarenflurbil | RAR/RXR |
| (R)-Flurbiprofen; MPC7869 | ||
| Tarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [3H]9-cis-RA to RXRα LBD with IC50 of 75 μM. | ||
| M15012 | Recombinant Human TIMP-2 (HEK293,C-6His) | Cytokines and Growth Factors |
| Metalloproteinase Inhibitor 2; CSC-21K | ||
| TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa. It produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-2 also has erythroid‑potentiating and cell growth promoting activities. | ||
| M16547 | Kaempferol 3-O-(3",6"-di-O-E- p-coumaroyl)-β-D-glucopyranoside | Flavonoids |
| Kaempferol 3-O-(3",6"-di-O-E- p-coumaroyl)-β-D-glucopyranoside | ||
| M17936 | Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside | Others |
| Kaempferol-3-O-α-L-rhamnopyranosyl-（1→6）-β-D-glucopyranosyl-（1→2）-β-D-glucopyranoside | ||
| M17961 | Kaempferol 3-O-(2''-O-α-rhamnosyl-6''-O-malonyl)-β-glucoside | Others |
| Kaempferol 3-O-（2''-O-α-rhamnosyl-6''-O-malonyl）-β-glucoside | ||
| M18054 | 6-Hydroxykaempferol 3,6-diglucoside | Others |
| 6-Hydroxykaempferol 3,6-diglucoside | ||
| M21336 | Recombinant Human MMP-9 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase | ||
| Recombinant human matrix metalloproteinase-9 is produced by a mammalian expression system and the target gene encoding Ala19-Asp707 has a 6His tag at the C-terminus. The proenzyme needs to be activated by APMA to form the active form. Protein ID: AAH06093.1. | ||
| M21684 | Recombinant Human MMP-3 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix metalloproteinase-3 | ||
| MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes. Recombinant Human Matrix Metalloproteinase-3 is produced by Mammalian expression system and the target gene encoding Tyr18-Cys477 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by Chymotrypsin for an activated form. | ||
| M21685 | Recombinant Human MMP-1 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix Metalloproteinase-1 | ||
| Matrix Metalloproteinase-1 (MMP-1) is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP-1 can degrade a broad range of substrates including types I, II, III, VII, VIII, and X collagens. The target gene encoding Phe20-Asn469 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by APMA for an activated form. | ||
| M27605 | Pentamidine | Parasite |
| MP-601205 | ||
| Pentamidine (MP-601205) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities. | ||
| M27723 | Amuvatinib hydrochloride | c-Kit |
| MP470 hydrochloride; HPK 56 hydrochloride | ||
| Amuvatinib hydrochloride (MP470 hydrochloride) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret. Amuvatinib hydrochloride (MP470 hydrochloride) is also a DNA repair suppressor through suppression of DNA repair protein RAD51, thereby disrupting DNA damage repair. Antineoplastic activity. | ||
| M30478 | Pentamidine dimesylate | Antibiotic |
| MP-601205 dimesylate | ||
| Pentamidine (MP-601205) dimesylate is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dimesylate inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine dimesylate is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dimesylate has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities. | ||
| M30893 | Indimitecan | Topoisomerase |
| LMP776 | ||
| Indimitecan (LMP776) is a topoisomerase I (Top1) inhibitor with anticancer activities. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
