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Tarenflurbil

Cat. No. M14524

All AbMole products are for research use only, cannot be used for human consumption.

Tarenflurbil Structure
Synonym:

(R)-Flurbiprofen; MPC7869

Price and Availability

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Quality Control & Documentation
Biological Activity

Tarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [3H]9-cis-RA to RXRα LBD with IC50 of 75 μM. Tarenflurbil can be used for Alzheimer's disease research.

Chemical Information
Molecular Weight 244.26
CAS Number 51543-40-9
Solubility (25°C) DMSO ≥ 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mukta Agrawal, et al. Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs

[2] Mary Sano. Tarenflurbil: mechanisms and myths

[3] Bruno Vellas. Tarenflurbil for Alzheimer's disease: a "shot on goal" that missed

[4] Xu Zhao, et al. Tarenflurbil protection from cytotoxicity is associated with an upregulation of neurotrophins

[5] Paul S Aisen. Tarenflurbil: a shot on goal

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  Catalog
Abmole Inhibitor Catalog




Keywords: Tarenflurbil, (R)-Flurbiprofen; MPC7869 supplier, RAR/RXR, inhibitors, activators

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