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Fenretinide (4-HPR) is a synthetic retinoid deriverative. Fenretinide is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death. Retinoids are substances related to vitamin A. Fenretinide has been investigated for potential use in the treatment of cancer, as well as in the treatment of cystic fibrosis, rheumatoid arthritis, acne, psoriasis, and has been found to also slow the production and accumulation of a toxin that leads to vision loss in Stargardt's patients.
| Molecular Weight | 391.55 |
| Formula | C26H33NO2 |
| CAS Number | 65646-68-6 |
| Solubility (25°C) | DMSO ≥ 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] N Hail Jr, et al. Mechanisms of fenretinide-induced apoptosis
[4] Marco Corazzari, et al. Fenretinide: a p53-independent way to kill cancer cells
[5] E Ulukaya, et al. Fenretinide and its relation to cancer
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| AGN 196996
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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