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Pentamidine dimesylate

Cat. No. M30478

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Pentamidine dimesylate Structure
Synonym:

MP-601205 dimesylate

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Quality Control & Documentation
Biological Activity

Pentamidine (MP-601205) dimesylate is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dimesylate inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine dimesylate is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dimesylate has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.

Chemical Information
Molecular Weight 532.63
Formula C21H32N4O8S2
CAS Number 6823-79-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] U Bronner, et al. Trans R Soc Trop Med Hyg. Pentamidine concentrations in plasma, whole blood and cerebrospinal fluid during treatment of Trypanosoma gambiense infection in Côte d'Ivoire

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Keywords: Pentamidine dimesylate, MP-601205 dimesylate supplier, Antibiotic, inhibitors, activators

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