About 30 results found for searched term "RP-1" (0.013 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1906 | Piclamilast | PDE |
| RP 73401 | ||
| Piclamilast (RP 73401) is a potent and selective inhibitor of phosphodiesterase (PDE) 4. | ||
| M1969 | Doxorubicin HCL | Animal Modeling |
| RP 13057 hydrochloride; Adriamycin; Rubex; DOX | ||
| Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. | ||
| M2312 | AG-1478 | EGFR/HER2 |
| Tyrphostin AG-1478 | ||
| AG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM. | ||
| M2327 | Daunorubicin hydrochloride | DNA/RNA Synthesis |
| Daunomycin hydrochloride; RP 13057 hydrochloride; Rubidomycin hydrochloride | ||
| Daunorubicin (Daunomycin) HCl is a topoisomerase II inhibitor, inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. | ||
| M2483 | Cabazitaxel | Others |
| XRP6258; RPR-116258A; taxoid XRP6258 | ||
| Cabazitaxel (XRP6258) is a semi-synthetic derivative of a natural taxoid. | ||
| M2647 | DMH1 | ALK |
| dorsomorphin homolog 1 | ||
| DMH1 is a selective BMP receptor inhibitor with IC50 of 107.9 nM for ALK2, exhibiting no inhibition on AMPK, ALK5, KDR (VEGFR-2) or PDGFR. | ||
| M3097 | Tyrphostin AG 1296 | VEGFR/PDGFR |
| AG 1296 | ||
| Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR. | ||
| M3397 | AG-1024 | IGF-1R |
| Tyrphostin AG 1024 | ||
| AG-1024 (Tyrphostin) inhibits IGF-1R autophosphorylation with IC50 of 7 μM, is less potent to IR with IC50 of 57 μM and specifically distinguishes between InsR and IGF-1R (as compared to other tyrphostins). | ||
| M3547 | Glibenclamide | Others |
| Glyburide; RP-1127; BIIB093 | ||
| Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). | ||
| M4880 | Tulathromycin B | Antibiotic |
| RP17833 | ||
| M4910 | Secnidazole | Parasite |
| PM 185184, RP 14539 | ||
| Secnidazole (flagellate) is a nitroimidazoles anti - infective compound. | ||
| M5046 | Imidafenacin (ONO-8025) | AChR/AChE |
| KRP-197; ONO-8025 | ||
| Imidafenacin (ONO-8025) is a urinary antispasmodic of the anticholinergic class.Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors (IC50=4.13 nM). | ||
| M5244 | Ozanimod | S1P Receptor |
| RPC1063 | ||
| Ozanimod (RPC1063) is a selective, orally active sphingosine-1-phosphate (S1P) receptor modulator that binds to S1PR1 and S1PR5, and can be used in studies related to ulcerative colitis (UC). | ||
| M5516 | Ciclesonide | GCR |
| Ciclesonide, Alvesco, Omnaris, RPR251526, Zetonna | ||
| Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. | ||
| M5834 | Oltipraz | HIF |
| RP 35972; NSC 347901 | ||
| Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). | ||
| M6463 | ARP 101 | Others |
| ARP 101 is a inhibitor of MMP-2. | ||
| M7214 | RP 001 hydrochloride | S1P Receptor |
| RP 001 hydrochloride is a potent S1P1 agonist. | ||
| M7397 | TCS PrP Inhibitor 13 | Others |
| TCS PrP Inhibitor 13 is a antiprion agent; inhibits PrP Sc accumulation. | ||
| M8146 | RPI-1 | RET |
| CS-2266 | ||
| RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor. | ||
| M8815 | Tyrphostin AG 1112 | Casein Kinase |
| Tyrphostin AG 1112 is a potent CK II inhibitor. In addition, Tyrphostin AG 1112 inhibited p210bcr-abl tyrosine kinase with IC50 values of 2 μM, 15 μM, and 20 μM against p210bcr-abl, EGFR, and PDGFR kinases, respectively, in cells. | ||
| M8818 | Tyrphostin RG 13022 | EGFR/HER2 |
| RG13022 | ||
| RG13022 is a non-phenolic tyrphostin-class tyrosine kinase inhibitor. | ||
| M8820 | Tyrphostin RG 14620 | Others |
| Tyrphostin RG14620 | ||
| Non-phenolic tyrphostin-class tyrosine kinase inhibitor. | ||
| M8827 | Tyrphostin 51 | Others |
| Tyrphostin 51 is an EGFR tyrosine kinase inhibitor. | ||
| M9300 | AG 126 | ERK |
| AG126; Tyrphostin AG 126 | ||
| AG 126 is a cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-α and nitric oxide in murine peritoneal macrophages. | ||
| M9374 | Fmoc-Trp(1-Me)-OH | Others |
| Fmoc-Trp(Me)-OH | ||
| Fmoc-Trp(1-Me)-OH is synthesized by N-(9-Fluorenylmethoxycarbonyloxy)succinimide (Fmoc-ONSu) and 1-Methyl-Ltrypthophan. | ||
| M9857 | TRP-14 | Peptides |
| TRAP; SFLLRNPNDKYEPF; ThroMbin Receptor Agonist Peptide | ||
| Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe is a synthetic thrombin receptor agonist peptide. | ||
| M9935 | β-Endorphin (27-31) (human) | Peptides |
| TYR-LYS-LYS-GLY-GLU | ||
| H-Tyr-Lys-Lys-Gly-Glu-OH; b-Endorphin (27-31) (human); TYR-LYS-LYS-GLY-GLU; β-Endorphin (27-31) (human) | ||
| M10229 | Porcine dynorphin A (1-13) | Opioid Receptor |
| Dynorphin A Porcine Fragment 1-13 | ||
| Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist. | ||
| M10559 | Tyrphostin A1 | IL Receptor/Related |
| Tyrphostin 1 | ||
| Tyrphostin A1 is a weaker EGFR tyrosine kinase inhibitor, Tyrphostin A1 inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells. | ||
| M10563 | Dynorphin A (1-8) | Opioid Receptor |
| H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH; YGGFLRRI | ||
| Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. Dynorphin A (1-8) inhibited 3H-Bremazocine binding to the purified kappa receptor with IC50 of 303 nM. | ||
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