About 30 results found for searched term "PSI" (0.024 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2007 | Romidepsin (FK228) | HDAC |
| FK228; ISTODAX; Depsipeptide; FR 901228; NSC 630176 | ||
| Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended | ||
| M2497 | Cathepsin Inhibitor 1 | Cathepsin |
| Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. | ||
| M3666 | Sofosbuvir (PSI-7977) | HCV Protease |
| Sofosbuvir, GS-7977 | ||
| Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM. | ||
| M1562 | PSI-6206 | Anti-infection |
| RO 2433; RO2433; RO-2433 | ||
| PSI-6206 is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. PSI-6206 low potently inhibits HCV replicon with EC90 of >100 μM. | ||
| M5373 | 6-Aminocaproic acid | Others |
| EACA; Epsilon-Amino-n-caproic Acid; 6-Aminohexanoic acid | ||
| 6-Aminocaproic acid (EACA) is a derivative and analogue of the amino acid lysine, it is also a potent and orally active inhibitor of plasmin and plasminogen. | ||
| M6236 | CA-074 Me | Cathepsin |
| Cathepsin B Inhibitor IV;CA-074 methyl ester | ||
| CA-074 Me is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor. | ||
| M7409 | Thapsigargin | Calcium Channel |
| Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase. | ||
| M7974 | Netropsin dihydrochloride | Others |
| Netropsin is an unusual n-methylpyrrole-containin |
||
| M9546 | TBK1/IKKε-IN-5 | IκB/IKK |
| ABM-7653; TBK1/IKK-epsilon-IN-5 | ||
| TBK1/IKKε-IN-5 (compound 1) is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively. | ||
| M21600 | Plitidepsin | DNA/RNA Synthesis |
| Aplidine | ||
| Plitidepsin (Aplidine) is a potent anticancer compound targeting eEF1A2 (KD=80 nM). Plitidepsin has antiviral activity, and the IC90 of inhibiting SARS-CoV-2 is 0.88 nM. Plitidepsin is commonly used in multiple myeloma and advanced cancer research and has potential for COVID-19 research. | ||
| M9708 | Chymotrypsin | Enzymes & Coenzymes |
| α-Chymotrypsin | ||
| α-Chymotrypsin is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges. | ||
| M9892 | Trypsin Inhibitor (from chicken egg white) | Peptides |
| Trypsin inhibitor from chicken egg white has been used to produce denatured, oxidized and deglycosylated ovomucoid and used to stimulate patient derived cell cultures for mapping T cell epitopes. | ||
| M9931 | ε-Viniferin | Cytochrome P450 (e.g. CYP17) |
| epsilon-Viniferin | ||
| ε-Viniferin is a potent inhibitor for all the CYP family, with Ki values from 0.5-20 μM. | ||
| M10184 | Trypsin (porcine pancreas) | Enzymes & Coenzymes |
| Trypsin is a serine protease in the digestive system of human and animals. The main function of this enzyme is to hydrolyze proteins into smaller peptides or even amino acids. | ||
| M11252 | Recombinant Human Cathepsin B (CHO，His) | Recombinant Proteins |
| Cathepsin B; APP secretase; APPS | ||
| Cathepsin B is an enzymatic protein that is a member of the peptidase (or protease) family. | ||
| M13485 | PSI-7409 | Anti-infection |
| PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977). Sofosbuvir (PSI-7977) is a selective and highly active nucleotide analog inhibitor of HCV. | ||
| M13859 | Epsilon-V1-2 | PKC |
| ε-V1-2; EAVSLKPT | ||
| Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor. Epsilon-V1-2 inhibits the translocationof PKCε, but not α-, β-, and δPKC. | ||
| M14757 | PSI-697 | Others |
| P-Selectin Inhibitor | ||
| PSI-697 is an oral P-selectin inhibitor with an IC50 of 125 μM. | ||
| M15059 | Psicofuranine | Antibiotic |
| Psicofuramine is a nucleoside antibiotic produced by the hygroscopic Streptomyces strain Bitter fungus. It has antifungal activity against Gram-positive bacteria and mycobacterium, and has antifungal activity against Walker cancer 256 in rats and Ca755 in mice. | ||
| M16244 | Maesopsin | Chalcones |
| Maesopsin | ||
| M16275 | O-Methylcedrelopsin | Coumarins |
| O-Methylcedrelopsin | ||
| M16305 | Cedrelopsin | Coumarins |
| Cedrelopsin | ||
| M16366 | 6-Dehydroxy-8-hydroxygaleopsinolone | Diterpenoids |
| 6-Dehydroxy-8-hydroxygaleopsinolone | ||
| M17163 | (+)-Isoampelopsin F | Phenols |
| (+)-Isoampelopsin F | ||
| M17522 | 4,5-Diepipsidial A | Sesquiterpenoids |
| 4,5-Diepipsidial A | ||
| M17593 | Psidial A | Sesquiterpenoids |
| Psidial A | ||
| M17915 | Drimiopsin C | Xanthones |
| Drimiopsin C | ||
| M17916 | Drimiopsin D | Xanthones |
| Drimiopsin D | ||
| M18093 | Psi-Taraxasterol / ψ-taraxasterol | Others |
| Psi-Taraxasterol / ψ-taraxasterol | ||
| M19103 | Thermopsine | Others |
| Thermopsine | ||
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