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 About 30 results found for searched term "Lipids" (0.093 seconds)

Cat.No.  Name Target
M2450 Bergapten Autophagy
5-Methoxypsoralen
Bergapten is a psoralen that can be photoactivated and is capable of crossing-linking DNA, covalently modifying proteins and lipids, and consequently inhibiting cell replication.
M11199 Myriocin Anti-infection
Thermozymocidin; ISP-I
Myriocin, a fungal metabolite isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent serine-palmitoyl-transferase Inhibitors are the key to the synthesis of sphingolipids from scratch.
M5121 DiO perchlorate Fluorescent Dye
DiOC18(3)
DiO or DiOC18(3) is one of the most commonly used cell membrane fluorescent probes, showing green fluorescence. It's used to look at cell membranes, lipids. Store at room temperature away from light.
M6890 Lalistat 2 Others
Lalistat 2 is a selective LAL inhibitor. Lalistat 2 is an inhibitor of many lipases especially Lysosomal acid lipase (LAL, IC50 = 152 nM), which is a key enzyme that degrades neutral lipids at an acidic pH in lysosomes.
M7528 Phosphatase Inhibitor Cocktail (EDTA-Free) Inhibitor Cocktails
AbMole Phosphatase Inhibitor Cocktail (EDTA-Free) is a mixture of phosphatase inhibitors prepared by 8 independent phosphatase inhibitors according to the optimized ratio. It is divided into A and B two tubes: A tube is a phosphate - root analogue to prevent the loss of phosphorylation of proteins and lipids, and B tube is a new natural product to provide more comprehensive protection for phosphorylation.
M7550 N-Acetylneuraminic acid Metabolite/Endogenous Metabolite
NANA; Lactaminic acid
N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies suggest that N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition.
M9227 Arachidonic acid Metabolite/Endogenous Metabolite
Immunocytophyte
Arachidonic acid (AA) is an unsaturated ω6 fatty acid constituent of the phospholipids of cell membranes.
M9379 DiD perchlorate Fluorescent Dye
DiD
The lipophilic carbocyanate DiD is an analog with a longer wavelength than DiI. Maximum excitation/emission wavelength is 644nm/665nm, red fluorescence, used to observe cell membranes, lipids. Store at room temperature away from light.
M9850 ABDP 493/503 Fluorescent Dye
ABDP 493/503 (same as BODIPY 493/503) is a lipophilic fluorescent probe that localizes to polar lipids and can be used to label cellular neutral lipid contents, particularly those localized to lipid droplets, in live and fixed cells.
M10154 Choline Glycerophosphate AChR/AChE
Choline Alfoscerate
Choline Glycerophosphate is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue.
M10649 DL-α-Tocopherol (Liquid) Vitamin
(±)-α-Tocopherol
DL-α-Tocopherol is used as an antioxidant that protects cell membrane lipids from oxidative damage.
M11521 DiOC6(3) iodide Fluorescent Dye
3,3'-Dihexyloxacarbocyanine iodide
DiOC6(3)(iodide 3,3' -dihexyl carbonyl cyanine) is a carbonyl cyanine dye that can be used to detect changes in mitochondrial membrane potential. The maximum excitation/emission wavelength is 484nm/500nm. It can be used to look at cell membranes, lipids. Store at room temperature away from light.
M14086 Glucosamine hydrochloride Metabolite/Endogenous Metabolite
D-(+)-Glucosamine hydrochloride; Chitosamine hydrochloride
Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement.
M14346 3-Hydroxybutyric acid Metabolite/Endogenous Metabolite
β-Hydroxybutyric acid
3-Hydroxybutyric acid (β-Hydroxybutyric acid) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid can modulate the properties of membrane lipids.
M14347 3-Hydroxybutyric acid sodium Metabolite/Endogenous Metabolite
β-Hydroxybutyric acid sodium
3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids.
M14375 Glucosamine Metabolite/Endogenous Metabolite
D-Glucosamine; Chitosamine
Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement.
M14438 Castanospermine Others
Castanospermine inhibits all forms of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids).
M14584 Glucosamine sulfate Metabolite/Endogenous Metabolite
D-Glucosamine sulfate
Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement.
M20681 Sphingosine Metabolite/Endogenous Metabolite
D-erythro-Sphingosine; erythro-C18-Sphingosine
Sphingosine (D-erythro-Sphingosine, Erythrosphingosine) is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important phospholipid.
M21527 MES hydrate Solvents & Excipients
MES is a buffer solution. MES is an amphoteric ion N- substituted sulfamic acid with a morpholine ring. This composition does not form complexes with most metals used in environmental and biological research. It is soluble in water but extremely insoluble in lipids, and therefore unable to penetrate membranes.
M22460 UDP-glucuronic acid trisodium Others
UDPGA trisodium
UDP-​glucuronic acid (UDPGA) trisodium is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.
M22498 CKK-E12 (Liquid) Liposome
CKKE12
CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. CKK-E12 was highly selective toward liver parenchymal cell in vivo.
M22499 C12-200 Liposome
C12200
C12-200 is a benchmark ionizable cationic lipidoid along with helper lipids. C12-200 is commonly used for mRNA delivery.
M24680 Evinacumab Others
REGN1500
Evinacumab (REGN1500) is a humanised anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia.
M25092 Recaticimab PCSK9
SHR-1209
Recaticimab (SHR-1209) is a humanized monoclonal antibody that inhibits PCSK9. Receticimab mediates the degradation of PCSK9 by binding to PCSK9, increasing the level of low-density lipoprotein (LDL) receptors on the surface of hepatocytes, reducing the level of LDL in plasma, and achieving the goal of lowering blood lipids. Recaticimab has potential application in hypercholesterolemia.
M25517 LAH4 TFA Cell Transfection
LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes.
M27789 D-threo-PDMP  Glucosylceramide Synthase
D-threo-PDMP is a potent glucoceramide synthase (GCS) inhibitor, which reduces the glycosphingolipids on the cell surface by inhibiting glycosylation, reduces the total length of the axon plexus and the number of axon branch points, and inhibits neurite growth.
M27807 Propargylcholine bromide  Others
Propargylcholine bromide is a choline analogue containing terminal propargyl that can be incorporated into all classes of Choline-containing phospholipids such as phosphatidylcholine and sphingomyelin, labeling Choline-containing phospholipids. Propargylcholine bromide-labeled phospholipid molecules can be visualized in cells with high sensitivity and spatial resolution. Propargylcholine bromide can be used as a molecular tool to study the biochemical and metabolic processes of Choline-containing phospholipids in cells.
M28223 Tetrahydrofolic acid Metabolite/Endogenous Metabolite
L-5,6,7,8-Tetrahydrofolic acid; L-Tetrahydrofolic acid
Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid) is the biologically active vitamin B9 folate derivative. Tetrahydrofolic acid is a donor of one-carbon groups for amino acids, nucleic acids, and lipids. Tetrahydrofolic acid serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid.
M30027 Phosphatidylinositols, soya, sodium salts  Others
Phosphatidylinositols, soya, sodium salts is a mixture of phosphatidylinositols. Phosphoinositides are lipids involved in the vesicular transport of proteins and lipids between the different compartments of eukaryotic cells. They act by recruiting and/or activating effector proteins and thus are involved in regulating various cellular functions, such as vesicular budding, membrane fusion and cytoskeleton dynamics.



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