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Evinacumab

Cat. No. M24680

All AbMole products are for research use only, cannot be used for human consumption.

Evinacumab Structure
Synonym:

REGN1500

Price and Availability

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Quality Control & Documentation
Biological Activity

Evinacumab (REGN1500) is a humanised anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia.

Chemical Information
CAS Number 1446419-85-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] No authors listed. Evinacumab

[2] No authors listed. Evinacumab

[3] Anthony Markham. Drugs. Evinacumab: First Approval

[4] Robert S Rosenson, et al. N Engl J Med. Evinacumab in Patients with Refractory Hypercholesterolemia

[5] Frederick J Raal, et al. N Engl J Med. Evinacumab for Homozygous Familial Hypercholesterolemia

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Keywords: Evinacumab, REGN1500 supplier, inhibitors, activators

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