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Lalistat 2 is a selective Lysosomal acid lipase inhibitor (IC50 = 152 nM). Lalistat 2 exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 μM). Lalistat 2 is commonly used to investigate the cell-specific functions of LAL and LAL deficiency in vitro, as well as specifically measure LAL activity in human blood samples or cells.
| Molecular Weight | 296.39 |
| Formula | C13H20N4O2S |
| CAS Number | 1234569-09-5 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Lin, et al. Nat Methods. A chemical platform for improved induction of human iPSCs.
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