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3-Hydroxybutyric acid (β-Hydroxybutyric acid) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid can modulate the properties of membrane lipids.
| Molecular Weight | 104.1 |
| CAS Number | 300-85-6 |
| Solubility (25°C) | Water 100 mg/mL 0.1 M NaOH 90 mg/mL (ultrasonic and adjust pH to 6 with NaOH) |
| Storage | 2-8°C, dry, sealed |
[1] Lian Wang, et al. β-hydroxybutyrate as an Anti-Aging Metabolite
[3] John C Newman, et al. β-Hydroxybutyrate: A Signaling Metabolite
[4] John C Newman, et al. Ketone bodies as signaling metabolites
| Related Metabolite/Endogenous Metabolite Products |
|---|
| 4-Hydroxyestrone
4-Hydroxyestrone (4-OHE1) is an estrone metabolite, it has strong neuroprotective effect against oxidative neurotoxicity. 4-Hydroxyestrone increases cytoplasmic translocation of p53 resulting from SIRT1-mediated deacetylation of p53. |
| SR-4995
SR-4995 is a potent and selective ligand of α-β-hydrolase domain containing 5 (ABHD5) that activates adipose triglyceride lipase (ATGL) by dissociating ABHD5 from its inhibitory regulator, perilipin-1 (PLIN1) and PLIN5. SR-4995 directly binds to ABHD5 and prevents ABHD5 to PLIN1. SR-4995 induces lipolysis in adipocytes and muscle, avoiding PKA-dependent signaling. |
| NAD sodium
NAD sodium (β-Nicotinamide adenine dinucleotide sodium salt) is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP. |
| L-Leucyl-L-Leucine methyl ester hydrochloride
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrochloride, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrochloride also can induce endolysosomal pathway stress. |
| 8-Hydroxyguanosine
8-Hydroxyguanosine is a marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. 8-Hydroxyguanosine is a purine nucleoside, it stimulates proliferation and differentiation of B cells. |
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