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Tetrahydrofolic acid

Cat. No. M28223

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Tetrahydrofolic acid Structure
Synonym:

L-5,6,7,8-Tetrahydrofolic acid; L-Tetrahydrofolic acid

Size Price Availability Quantity
5mg USD 32  USD32 In stock
10mg USD 50  USD50 In stock
25mg USD 70  USD70 In stock
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Quality Control & Documentation
Biological Activity

Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid) is the biologically active vitamin B9 folate derivative. Tetrahydrofolic acid is a donor of one-carbon groups for amino acids, nucleic acids, and lipids. Tetrahydrofolic acid serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid.

*The compound is unstable in solutions, freshly prepared is recommended

Chemical Information
Molecular Weight 445.43
Formula C19H23N7O6
CAS Number 135-16-0
Form Solid
Solubility (25°C) DMSO 20.83 mg/mL (ultrasonic)
Storage -20°C, protect from light, sealed
References

[1] Mark R Sullivan, et al. Nat Metab. Methionine synthase is essential for cancer cell proliferation in physiological folate environments

[2] Elysia Tjong, et al. Biochemistry, Tetrahydrofolate

[3] Clara B García-Calderón, et al. Cell Death Differ. Genotoxicity of tetrahydrofolic acid to hematopoietic stem and progenitor cells

[4] Raphael J Morscher, et al. Nature. Mitochondrial translation requires folate-dependent tRNA methylation

[5] Francisco García-Molina, et al. J Agric Food Chem. Tetrahydrofolic Acid is a potent suicide substrate of mushroom tyrosinase

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Keywords: Tetrahydrofolic acid, L-5,6,7,8-Tetrahydrofolic acid; L-Tetrahydrofolic acid supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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