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About 13 results found for searched term "Integrase" (0.04 seconds)
| Cat.No. | Name | Information |
|---|---|---|
| M1681 | BMS-707035 | BMS-707035 is an HIV-1 integrase (IN) inhibitor. HIV-1 integrase (IN) represents a therapeutically advantageous viral target to treat HIV/AIDS in the clinic. |
| M1979 | Elvitegravir | Elvitegravir (EVG) is a HIV integrase inhibitor with IC50 of 0.7 nM, 2.8 nM and 1.4 nM for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD, respectively. |
| M2595 | Raltegravir | Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM, respectively. |
| M3195 | MK-2048 | MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively. |
| M3484 | Dolutegravir | Dolutegravir (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. |
| M4752 | l-Chicoric-acid | L-chicoric Acid ((-)-Chicoric Acid), a dicafoyl tartaric Acid, is a potent, selective and reversible INHIBITOR of HIV-1 integrase with an IC50 of approximately 100 nM. L-chicoric Acid also inhibits HIV-1 replication in tissue cultures. |
| M4824 | Dolutegravir sodium | Dolutegravir sodium is a potent, second generation HIV integrase inhibitor (IC₅₀ = 2.7 nM) that displays potent antiviral activity. |
| M5084 | Raltegravir potassium | Raltegravir potassium (MK0518 potassium) is a potent integrase (IN) inhibitor, used to treat HIV infection. |
| M9113 | Bictegravir | Bictegravir (GS-9883) is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. |
| M9491 | BMS-538203 | BMS-538203 is a highly efficient HIV integrase inhibitor and antiviral agent. |
| M10371 | Cabotegravir | Cabotegravir, also known as S/GSK1265744 or GSK744, is potent HIV integrase inhibitor. |
| M20765 | Lavendustin B | Lavendustin B inhibits HIV-1 integrase (IN) interaction with its cognate cellular cofactor lens epithelium-derived growth factor (LEDGF/p75). Lavendustin B is an inhibitor of Tyrosine Kinase and also a competitive inhibitor of glucose transporter 1 (Glut1). |
| M20886 | Bictegravir Sodium | Bictegravir (GS-9883) Sodium is a novel and potent inhibitor of HIV-1 integrase, specifically targets IN strand transfer activity with an IC50 of 7.5 nM. |
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