All AbMole products are for research use only, cannot be used for human consumption.
For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.
D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells). IC50 value: 23.8 μg/ml (EC50, in MT-4 cell ), 5.03 μg/ml (EC50, in C8166 cell) Target: HIV-1 in vitro: D77 exhibits a highly specific binding affinity to HIV-1 integrase catalytic core domain.D77 induces a dramatic concentration-dependent decrease of α-galactosidase activity compared to the D77-untreated cells. D77 reveals a significant inhibition activity against the interaction of IN with IBD.
| Molecular Weight | 596.45 |
| Formula | C28H22BrNO7S |
| CAS Number | 497836-10-9 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] Tobias Madl. Acta Crystallogr D Struct Biol. Intracellular drug binding affinities by NMR
| Related HIV Protease Products |
|---|
| Bevirimat
Bevirimat (BVM), also known as PA-457 or MPC-4326, is a novel Human Immunodeficiency Virus type 1 (HIV-1) maturation inhibitor. |
| Delavirdine mesylate
Delavirdine mesylate is a nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1). |
| BMS-663068
BMS-663068 is a novel small-molecule attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells with EC50 of < 10 nM. |
| Des(benzylpyridyl) Atazanavir
Des(benzylpyridyl) Atazanavir is a HIV protease inhibitor, the N-dealkylated metabolite (M1) of Atazanavir (A790051). |
| Salicylanilide
Salicylanilides are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
