About 30 results found for searched term "INH1" (0.012 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1859 | RepSox | ALK |
| ALK5 Inhibitor II; E-616452; SJN 2511 | ||
| RepSox (ALK5 Inhibitor II) is a potent and ATP-competitive inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively). | ||
| M2040 | BAY 11-7082 | IκB/IKK |
| BAY 11-7821; NF-κB inhibitor 13 | ||
| BAY 11-7082 is an inhibitor of cytokine-induced IκB-α phosphorylation (IC50 ~ 10 μM). BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 μM, respectively). | ||
| M2076 | SP600125 | JNK |
| JNK Inhibitor II; 1PMV; NSC75890; Pyrazolanthrone | ||
| SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM. | ||
| M2085 | Tie2 kinase inhibitor | Others |
| Tie2 kinase inhibitor 1; compound 5 | ||
| Tie2 kinase inhibitor is a potent, reversible, and ATP-binding site-targeting Tie2 inhibitor with an IC50 of 250 nM. | ||
| M2114 | GSK126 | EZH2 |
| EZH2 inhibitor; GSK2816126A | ||
| GSK126 is a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase activity. | ||
| M2497 | Cathepsin Inhibitor 1 | Cathepsin |
| Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. | ||
| M2504 | CFTR(inh)-172 | CFTR |
| CFTR inhibitor 172 | ||
| CFTR(inh)-172 is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, showing no effects on MDR1, ATP-sensitive K+ channels, or a series of other transporters. | ||
| M2830 | Mdivi-1 | Dynamin |
| Mitochondrial division inhibitor 1 | ||
| Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. | ||
| M2978 | RI-1 | RAD51 |
| RAD51 inhibitor 1 | ||
| RI-1 is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM. | ||
| M3054 | TDZD-8 | GSK-3 |
| GSK-3β Inhibitor I; NP 01139 | ||
| TDZD-8 is a non-ATP competitive GSK-3β inhibitor with IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC. | ||
| M1261 | NFAT Inhibitor-1 (VIVIT peptide) | NFAT |
| VIVIT peptide; ABM-7733 | ||
| NFAT Inhibitor-1 (VIVIT peptide) is a cell-permeable peptide inhibitor of nuclear factor of activated Tcells (NFAT), it is superior at inhibiting calcineurin-mediated dephosphorylation of NFAT1, NFAT2, and NFAT4 in cell extracts. | ||
| M5293 | Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO) | Inhibitor Cocktails |
| Protease inhibitor cocktails are used in mammalian cell lysates or tissue extracts to increase protein stability. | ||
| M5347 | Y15 | FAK |
| FAK inhibitor Y15; FAK Inhibitor 14 | ||
| Y15 is a novel small molecule FAK phosphorylation inhibitor; specifically block phosphorylation of Y397-FAK and total phosphorylation of FAK. | ||
| M6554 | CaCCinh-A01 | Chloride Channel |
| CaCCinh-A01 is a calcium-activated chloride channel (CaCC) inhibitor. | ||
| M6830 | INH1 | Others |
| IBT13131 | ||
| INH1 is a hec1 inhibitor; causes arrest of mitosis. | ||
| M7346 | T16Ainh-A01 | Chloride Channel |
| T16Ainh-A01 is a Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A) inhibitor. | ||
| M7397 | TCS PrP Inhibitor 13 | Others |
| TCS PrP Inhibitor 13 is a antiprion agent; inhibits PrP Sc accumulation. | ||
| M8160 | Src Inhibitor-1 | Src-bcr-Abl |
| Src Kinase Inhibitor 1; Src-l1 | ||
| Src interactivator-1 is a highly selective, ATP-competitive, two-site Src tyrosine kinase Inhibitor with IC50 values of 44 nM and 88 nM against Src and Lck, respectively. Src interactivator-1 also inhibits Csk and Yes. | ||
| M8206 | PDI inhibitor 16F16 | Others |
| 16F16 is a protein disulfide isomerase (PDI) inhibitor, first identified in a screen for compounds that prevent apoptosis induced by mutant huntingtin protein. | ||
| M8562 | SID 3712249 | Others |
| MiR-544 Inhibitor 1 | ||
| SID 3712249 (MiR-544 Inhibitor 1) is an inhibitor of the biogenesis of microRNA-544 (miR-544). | ||
| M8959 | BMS-1 (PD-1/PD-L1 inhibitor 1, PD1-PDL1-IN1) | PD-1/PD-L1 |
| BMS-1 (PD-1/PD-L1 inhibitor 1, PD1-PDL1-IN1) is an inhibitor of PD-1/PD-L1 protein/protein interaction with an IC50 of 6 to 100 nM. | ||
| M9098 | HDAC8-IN-1 | HDAC |
| ABM-7933; HDAC8 inhibitor 1 | ||
| HDAC8-IN-1 is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. | ||
| M9126 | Ac-CoA Synthase Inhibitor 1 | Anti-infection |
| Ac-CoA Synthase Inhibitor I | ||
| Ac-CoA Synthase Inhibitor 1 (also known as ACSS2 Inhibitor), an anti-virus agent, is a Ac-CoA Synthase Inhibitor. | ||
| M9279 | LW6 | HIF |
| HIF-1α inhibitor; CAY10585 | ||
| LW6 is a novel HIF-1alpha inhibitor, with an IC50 of 4.4 μM. LW6 decreases HIF-1α protein expression without affecting HIF-1β expression. | ||
| M9395 | HG-9-91-01 | Salt-inducible Kinase |
| SIK inhibitor 1 | ||
| HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIK) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively. | ||
| M9403 | TPI-1 | Phosphatase |
| Tyrosine Phosphatase Inhibitor 1 | ||
| TPI-1 is a SHP-1 inhibitor, inhibits recombinant SHP-1 with an IC50 of 40 nM. | ||
| M9492 | B-Raf inhibitor 1 | Raf |
| ABM-0403 | ||
| B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 µM and 2 nM for A375 proliferation and A375 p-ERK, respectively. | ||
| M9505 | Compound E | Gamma-secretase/Beta-secretase |
| GSI-XXI; γ-secretase inhibitor XXI; γ-Secretase-IN-1 | ||
| Compound E is a cell-permeable, potent, selective inhibitor of γ-secretase and Notch processing. | ||
| M9537 | Protein kinase inhibitors 1 | DYRK |
| Protein kinase inhibitors I | ||
| Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM. | ||
| M9730 | B7/CD28 interaction inhibitor 1 | Immunology/Inflammation |
| ABM-24720; CTLA-4 - inhibitor | ||
| B7/CD28 interaction inhibitor 1 is a potent B7.1-CD28 interaction inhibitor with IC50 of 50 nM. | ||
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