About 27 results found for searched term "Ginsenoside-Re" (0.137 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4074 | Ginsenoside-Re | Amyloid |
| Ginsenoside B2; Panaxoside Re; Chikusetsusaponin IVc; Sanchinoside Re | ||
| Ginsenoside Re (Ginsenoside B2) is a ginseng - ginseng extract. Ginsenoside Re reduces beta-amyloid (Aβ). Ginsenoside Re also exerts anti-inflammatory effects by inhibiting JNK and NF-κB. | ||
| M3940 | Ginsenoside Rg1 | Amyloid |
| G-Rg1; Panaxoside Rg1 | ||
| Ginsenoside Rg1 is part of a class of triterpene saponins and steroid glycosides. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. It is found exclusively in the plant genus Panax, or ginseng. | ||
| M3987 | Ginsenoside Rb1 | Sodium Channel |
| Gynosaponin C; Gypenoside III | ||
| Ginsenoside Rb1 is an ingredient in the Chinese medicine Panax ginseng. Ginsenoside inhibition Na, K-ATPase++ activityIC50 6.3±1.0 μM. Ginsenoside Rb1 also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. | ||
| M4064 | Pseudoginsenoside-F11 | Metabolite/Endogenous Metabolite |
| Ginsenoside A1 | ||
| Pseudoginsenoside F11 (Ginsenoside A1), a component of Panax quinquefolium, can resist the learning and memory impairment induced by scopolamine, morphine and methamphetamine in mice. | ||
| M4065 | Ginsenoside-Rb2 | Anti-infection |
| Ginsenoside C | ||
| Ginsenoside Rb2 is one of the main bioactive components of ginseng extract. Ginsenoside Rb2 can up-regulate GPR120 gene expression. Ginsenoside Rb2 has antiviral effects. | ||
| M4068 | Ginsenoside-Rg3 | Sodium Channel |
| 20(S)-Ginsenoside-Rg3; Rg3; S-Ginsenoside Rg3 | ||
| 20(S)-Ginsenoside Rg3 is the main ingredient of red ginseng. 20(S) -ginsenoside Rg3 inhibited Na+ and hKv1.4 channels with IC50 of 32.2±4.5 and 32.6±2.2 μM, respectively. 20(S) -ginsenoside Rg3 also inhibited Aβ, NF-κB activity and COX-2 expression. | ||
| M4069 | (S)Ginsenoside-Rh1 | PPAR |
| Prosapogenin A2; Sanchinoside B2; Sanchinoside Rh1; Ginsenoside-Rh1 | ||
| Ginsenoside Rh1 (Prosapogenin A2) inhibited the expression of PPAR-γ, TNF-α, IL-6 and IL-1β. | ||
| M4072 | Ginsenoside-Rh3 | Keap1-Nrf2 |
| Ginsenoside Rh3 is a bacterial metabolite of Ginsenoside Rg5. Ginsenoside Rh3 induces Nrf2 activation in human retinal cells. | ||
| M4073 | Ginsenoside-Rc | GABA Receptor |
| Panaxoside Rc | ||
| Ginsenoside Rc is one of the major ginsenosides. Ginsenoside Rc enhances GABA receptor A (GABAA) -mediated ion channel (IGABA) currents. Ginsenoside Rc also inhibited TNF-α and IL-1β expression. | ||
| M4075 | Ginsenoside-Rd | NF-κB |
| Gypenoside VIII | ||
| Ginsenoside Rd inhibited NF-κB transcriptional activity induced by TNFα with IC50 of 12.05±0.82 μM. Ginsenoside Rd inhibited the expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibited CYP2D6, CYP1A2, CYP3A4 and CYP2C9 with IC50 of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM and 85.1±9.1 μM, respectively. | ||
| M4078 | (R)Ginsenoside-Rh1 | Others |
| (R)Ginsenoside-Rh1 is one of the important protopanaxatriol ginsenosides and has been reported to be the main hydrolysis product reaching the systemic circulation after oral ingestion of ginseng. | ||
| M4079 | (R)Ginsenoside-Rh2 | MMP |
| 20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as an anti-proliferative agent in cells. It has anticancer effects by blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis and has anti-inflammatory and antioxidant activities. 20(R)-Ginsenoside Rh2 inhibited the replication and proliferation of mouse and human γ herpevirus 68 (MHV-68) with an IC50 of 2.77 μM against mouse MHV-68. | ||
| M4082 | Protopanaxtriol | Others |
| 20(R)-APPT; 20(R)-Protopanaxatriol | ||
| 20(R)-Protopanaxatriol is a natural ginsenoside ligand of Re, Rf, Rg1, Rg2 and Rh. | ||
| M4084 | Ginsenoside-F2 | Apoptosis |
| Ginsenoside F2, a metabolite of Ginsenoside Rb1, induces apoptosis and protective autophagy in breast cancer stem cells. | ||
| M4085 | Ginsenoside-F3 | IL Receptor/Related |
| Ginsenoside F3, a saponin extracted from Panax ginseng leaves, exerts immune-enhancing activity by regulating the production and expression of il-2 (IFN-γ) and IL-4 and IL-10. | ||
| M4086 | Ginsenoside-F4 | Apoptosis |
| Ginsenoside F4 (GF4), Ginsenoside, isolated from Panax notoginseng or red ginseng. Ginsenoside F4 (GF4) can inhibit human lymphocytic tumor JK cells by inducing apoptosis. Ginsenoside F4 (GF4) inhibited the expression of matrix metalloproteinase 13 (MMP 13) in IL-1β -treated chondrocytes, blocked cartilage damage in rabbit cartilage tissue culture, and prevented cartilage collagen matrix decomposition in pathological tissues. | ||
| M4088 | Ginsenoside Compound-K | COX |
| Ginsenoside K; Ginsenoside C-K | ||
| Ginsenoside Compound-K is a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. | ||
| M4089 | Ginsenoside-Ro | Calcium Channel |
| Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V; Ginsenoside-Ro | ||
| Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) has the antiplatelet effect of Ca2+ antagonist with IC50 of 155 μM. Ginsenoside Ro decreased TXA2 production and Ginsenoside Ro also slightly decreased COX-1 and TXAS activity. | ||
| M4090 | Ginsenoside-Rg5 | IGF-1R |
| Ginsenoside Rg5 is the main ingredient of red ginseng. Ginsenoside Rg5 blocks the binding of IGF-1 to its receptor with an IC50 of about 90 nM. Ginsenoside Rg5 also inhibited COX-2 mRNA expression by inhibiting DNA binding activity of NF-κB P65. | ||
| M4092 | Ginsenoside-Rk1 | NF-κB |
| Ginsenoside Rk1 is a high-temperature processed extract of ginseng. Ginsenoside Rk1 has anti-inflammatory effects and inhibits Jak2/Stat3 signaling pathway and NF-κB activation. | ||
| M4101 | Notoginsenoside-R1 | Amyloid |
| Sanchinoside R1; Sanqi glucoside R1 | ||
| Notoginsenoside R1 (Sanchinoside R1) is a saponin isolated from P. notoginseng. Notoginsenoside R1 has antioxidant, anti-inflammatory, anti-angiogenic and anti-apoptotic activities. Notoginsenoside R1 provides cardiac protection against ischemia/reperfusion (I/R) injury. Notoginsenoside R1 may also provide neuroprotection. | ||
| M4104 | 20(S)-NotoginsenosideR2 | Apoptosis |
| 20(S)-Notoginsenoside R2; Ginsenoside Ng-R2 | ||
| Notoginsenoside R2(Notoginsenoside R2) is a newly isolated panax Notoginsenoside R2, which showed protective effects against oxidative stress and cell apoptosis induced by 6-OHDA. | ||
| M18476 | Notoginsenoside Fa | Others |
| Notoginsenoside Fa is a protopanaxadiol (ppd)-type saponin isolated from P. notoginseng, could possibly activate and recover the function of degenerated brain. | ||
| M18477 | Notoginsenoside Fc | Autophagy |
| Notoginsenoside Fc is a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy. | ||
| M39962 | Notoginsenoside FP2 | Others |
| Notoginsenoside FP2, a dammarane-Type Bisdesmoside isolated from the Fruit Pedicels of Panax notoginseng, has potential to treat cardiovascular disease. | ||
| M39971 | Vinaginsenoside R8 | Others |
| Vinaginsenoside R8, a triterpenoid glycoside isolated from the rhizomes of Panacis majoris. Vinaginsenoside R8 displays activities against adenosine diphosphate (ADP)-induced platelet aggregation (IC50=25.18 μM). | ||
| M40343 | Neopanaxadiol | Others |
| Neopanaxadiol, an aglycone of protopanaxadiol type ginsenosides, has the potential for Alzheimer's disease research. | ||
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