All AbMole products are for research use only, cannot be used for human consumption.
Ginsenoside-Rh2.png)
20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as an anti-proliferative agent in cells. It has anticancer effects by blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis and has anti-inflammatory and antioxidant activities. 20(R)-Ginsenoside Rh2 inhibited the replication and proliferation of mouse and human γ herpevirus 68 (MHV-68) with an IC50 of 2.77 μM against mouse MHV-68.
| Molecular Weight | 622.87 |
| Formula | C36H62O8 |
| CAS Number | 112246-15-8 |
| Solubility (25°C) | 10 mM in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Xun Li, et al. Anticancer property of ginsenoside Rh2 from ginseng
[3] Soowon Kang, et al. Antiviral activity of 20( R)-ginsenoside Rh2 against murine gammaherpesvirus
| Related MMP Products |
|---|
| KP-457
KP-457 is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, with IC50 of 11.1 nM (cell-free assay). KP-457 also cleaves various molecules such as GPIbα, GPV, and TNF-α. |
| MMP2-IN-1
MMP2-IN-1 is a moderate potenet MMP2 inhibitor with IC50 of 6.8 µM. MMP2-IN-1 exhibits remarkable antiproliferative activity in certain cancer cells by arresting the cell cycle and inducing apoptosis. |
| MMP-9 Inhibitor I
MMP-9 inhibitor I is a cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). MMP-9 inhibitor I also inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 IC50 = 113 nM) at higher concentrations. |
| BPHA
BPHA is a potent and orally active MMP-2, MMP-9 and MMP-14 inhibitor with IC50s of 12 nM, 16 nM and 17 nM, respectively. |
| ONO-4817
ONO-4817 is a potent inhibitor of matrix metalloproteinase (MMP). |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
