About 30 results found for searched term "MMP" (0.056 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7920 | MMPIP | Others |
| MMPIP is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7). | ||
| M9640 | MMP-9-IN-1 | MMP |
| ABM-7710 | ||
| MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor. | ||
| M21336 | Recombinant Human MMP-9 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase | ||
| Recombinant human matrix metalloproteinase-9 is produced by a mammalian expression system and the target gene encoding Ala19-Asp707 has a 6His tag at the C-terminus. The proenzyme needs to be activated by APMA to form the active form. Protein ID: AAH06093.1. | ||
| M21684 | Recombinant Human MMP-3 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix metalloproteinase-3 | ||
| MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes. Recombinant Human Matrix Metalloproteinase-3 is produced by Mammalian expression system and the target gene encoding Tyr18-Cys477 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by Chymotrypsin for an activated form. | ||
| M21685 | Recombinant Human MMP-1 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix Metalloproteinase-1 | ||
| Matrix Metalloproteinase-1 (MMP-1) is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP-1 can degrade a broad range of substrates including types I, II, III, VII, VIII, and X collagens. The target gene encoding Phe20-Asn469 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by APMA for an activated form. | ||
| M24708 | Andecaliximab | MMP |
| Anti-MMP9 Reference Antibody | ||
| Andecaliximab is a recombinant chimeric IgG4 monoclonal antibody (mAb) targets matrix metalloproteinase 9 (MMP9). Andecaliximab shows the antifibrotic efficacy in idiopathic pulmonary fibrosis mouse models. Andecaliximab can be used for the research of gastric adenocarcinoma and idiopathic pulmonary fibrosis (IPF). | ||
| M25487 | PU02 | 5-HT Receptor |
| NMMP | ||
| PU02 (NMMP) is a potent and selective negative allosteric modulator (NAM) of 5-HT3 receptor, displaying IC50 values of ~1 μM at 5-HT(3)Rs and substantially lower activities at other Cys-loop receptors. PU02 inhibits the proliferation of hepatocellular carcinoma (HepG2) cells associated with G2/M phase cell cycle arrest, and reduced cyclin-dependent kinase (CDK) 4 and cyclin B1/D1 levels. | ||
| M27972 | BI-4394 | MMP |
| MMP13-IN-3 | ||
| BI-4394 (MMP13-IN-3) is a potent, selective, and orally active MMP-13 inhibitor (IC50=1 nM[1]) for the potential treatment of osteoarthritis. BI-4394 is >1000 selective over other MMPs. | ||
| M28847 | MMP2-IN-2 | MMP |
| MMP2-IN-2 (compound 42) is a potent and selective MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC50 values of 12, 23.3, and 25 μM, respectively. | ||
| M31127 | Recombinant Human MMP-2 Protein (HEK293, C-6His) | Enzymes & Regulators |
| Matrix Metalloproteinase-2; Gelatinase A | ||
| Recombinant Human MMP-2 (also known as matrix metalloproteinase-2) is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. MMP-2 can act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. The proenzyme needs to be activated by APMA for an activated form. | ||
| M31128 | Recombinant Mouse MMP-2 Protein (HEK293, N-His) | Enzymes & Regulators |
| Matrix Metalloproteinase-2 | ||
| Matrix Metalloproteinase-2 (MMP-2) is an enzyme that plays a pivotal role in cell migration during physiological and pathological processes. The recombinant mouse MMP-2 consists 273 amino acids and predicts a molecular mass of 30.9 kDa. | ||
| M41050 | MmpL3-IN-2 | Antibiotic |
| MmpL3-IN-2 is an MmpL3 inhibitor with low cytotoxicity and moderate metabolic stability for tuberculosis research. | ||
| M41117 | MmpL3-IN-3 | Antibiotic |
| MmpL3-IN-3 is a MmpL3 inhibitor. | ||
| M42510 | MMP-8 inhibitor-1 | MMP |
| MMP-8 inhibitor-1, a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability. | ||
| M42511 | MMP13-IN-5 | MMP |
| MMP13-IN-5 is a potent and selective inhibitor of MMP-2/MMP-13 (IC50=3.6 μM/14.6 μM), involved in osteoarthritis (OA). | ||
| M42512 | MMP13-IN-4 | MMP |
| MMP13-IN-4 is a potent and selective inhibitor of MMP-13 (IC50=14.6 μM), involved in osteoarthritis (OA). | ||
| M42515 | MMP-9-IN-6 | MMP |
| MMP-9-IN-6 is a MMP-9 inhibitor with IC50 value of 50 μM, which has good anti-ulcer effect. | ||
| M42516 | MMP-13-IN-1 | MMP |
| MMP-13-IN-1 is a potent and selective inhibitor of MMP-13 with a IC50 value of 16 nM. | ||
| M42518 | MMP-7-IN-2 | MMP |
| MMP-7-IN-2 is a selective MMP7 inhibitor, with an IC50 of 16 nM. | ||
| M43969 | Recombinant Mouse MMP-12 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix metalloproteinase-12 | ||
| Matrix metalloproteinase-12 (MMP12) contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. | ||
| M43970 | Recombinant Human MMP-8 Protein (HEK293, C-His) | Enzymes & Regulators |
| Matrix metalloproteinase-8 | ||
| Matrix metalloproteinase-8 (MMP-8) is a member of the peptidase M1A family. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in dгυg development. | ||
| M43971 | Recombinant Human MMP12 Protein (E. coli) | Enzymes & Regulators |
| Matrix metalloproteinase-12 | ||
| Matrix metalloproteinase-12 (MMP12) is a macrophage-secreted elastase that is highly induced in the liver and lung in response to S. mansoni eggs and contains four hemopexin-like domains. MMP12 is a proteolytic enzyme responsible for the cleavage of plasminogen to angiotensin, which has an angiostatic effect. | ||
| M49671 | MMPP | STAT |
| MMPP is an anti-inflammatory agent. MMPP prevents LPS-induced mortality by inhibiting the inflammatory response via STAT3 activity inhibition. | ||
| M50179 | ARO-MMP7 | MMP |
| ARO-MMP7 is a small interfering RNA (siRNA) that reduces matrix metalloproteinase 7 (MMP7) expression and can be used in studies related to idiopathic pulmonary fibrosis (IPF). | ||
| M50842 | MMP-1 Substrate | Others |
| MMP-1 Substrate is a matrix metalloproteinase-1 (MMP-1) selective substrate that can be used for the fluorometric determination of MMP-1 enzymatic activity. | ||
| M51064 | MMP-2/MMP-9 Substrate | Others |
| MMP-2/MMP-9 Substrate, a synthetic colorimetric substrate, is a peptide. | ||
| M51697 | MMP-1/MMP-9 Substrate, Fluorogenic | Fluorescent Dye |
| MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9.Ex/Em = 340/440 nm. | ||
| M52564 | MMP3 inhibitor 3 | MMP |
| MMP3 inhibitor 3 is an inhibitor of MMP3. | ||
| M52565 | MMP-13 Substrate | MMP |
| MMP-13 Substrate is a substrate of MMP-13. | ||
| M52568 | MMP-8/MMP-26 Fluorogenic substrate | MMP |
| MMP-8/MMP-26 Fluorogenic substrate (DNP-Pro-Leu-Ala-Tyr-Trp-Ala-Arg) is a matrix metalloproteinase-8 (MMP-8) fluorogenic substrate. | ||
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