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Matrix metalloproteinase-12 (MMP12) contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity.
Recombinant Mouse Matrix Metalloproteinase 12 (MMP12) expressed the target gene encoding Ala29-Cys473 with a 6His tag at the C-terminus. The proenzyme needs to be activated by APMA for an activated form.
Accession: P34960
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 64 KDa, reducing conditions
Supplied as a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, 0.01%Tween80, 1mM EDTA, 50% Glycerol, pH6.0.
The product is shipped on dry ice. Upon receipt, store it immediately at the temperature listed below.
| Form | Solution |
| Storage | Store at ≤ -70°C, stable for 6 months after receipt. |
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| Recombinant Human MMP12 Protein (E. coli)
Matrix metalloproteinase-12 (MMP12) is a macrophage-secreted elastase that is highly induced in the liver and lung in response to S. mansoni eggs and contains four hemopexin-like domains. MMP12 is a proteolytic enzyme responsible for the cleavage of plasminogen to angiotensin, which has an angiostatic effect. |
| Recombinant Human MMP-8 Protein (HEK293, C-His)
Matrix metalloproteinase-8 (MMP-8) is a member of the peptidase M1A family. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in dгυg development. |
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Products are for research use only. Not for human use. We do not sell to patients.
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