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MMP2-IN-2 

Cat. No. M28847

All AbMole products are for research use only, cannot be used for human consumption.

MMP2-IN-2  Structure

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Quality Control & Documentation
Biological Activity

MMP2-IN-2 (compound 42) is a potent and selective MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC50 values of 12, 23.3, and 25 μM, respectively.

Chemical Information
Molecular Weight 284.23
Formula C13H8N4O4
CAS Number 1772-39-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Related MMP Products
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MMP2-IN-1 is a moderate potenet MMP2 inhibitor with IC50 of 6.8 µM. MMP2-IN-1 exhibits remarkable antiproliferative activity in certain cancer cells by arresting the cell cycle and inducing apoptosis.

MMP-9 Inhibitor I

MMP-9 inhibitor I is a cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). MMP-9 inhibitor I also inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 IC50 = 113 nM) at higher concentrations.

BPHA 

BPHA is a potent and orally active MMP-2, MMP-9 and MMP-14 inhibitor with IC50s of 12 nM, 16 nM and 17 nM, respectively.

ONO-4817 

ONO-4817 is a potent inhibitor of matrix metalloproteinase (MMP).

UK-370106 

UK-370106 is a potent and highly selective MMP-3 (IC50 of 23 nM) and MMP-12 (IC50 of 42 nM) inhibitor with >1200-fold higher potency than MMP-1, MMP-2, MMP-9, and MMP-14, and about 100-fold than MMP-13 and MMP-8.

  Catalog
Abmole Inhibitor Catalog




Keywords: MMP2-IN-2  supplier, MMP, inhibitors, activators

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