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Ginsenoside Rd inhibited NF-κB transcriptional activity induced by TNFα with IC50 of 12.05±0.82 μM. Ginsenoside Rd inhibited the expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibited CYP2D6, CYP1A2, CYP3A4 and CYP2C9 with IC50 of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM and 85.1±9.1 μM, respectively.
| Molecular Weight | 947.15 |
| Formula | C48H82O18 |
| CAS Number | 52705-93-8 |
| Solubility (25°C) | 10 mM in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Yu-Ying Chen, et al. Ginsenoside Rd: A promising natural neuroprotective agent
[4] Seyed Fazel Nabavi, et al. Ginsenoside Rd and ischemic stroke; a short review of literatures
[5] Ruidong Ye, et al. Ginsenoside Rd for acute ischemic stroke: translating from bench to bedside
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