About 16 results found for searched term "GST-IN-1" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M14444 | GSTO1-IN-1 | Others |
| GSTO1-IN-1 is a potent glutathione S-transferase omega 1 (GSTO1) inhibitor with an IC50 of 31 nM. | ||
| M42432 | GST-IN-1 | Transferase |
| GST-IN-1 is a glutathione S-transferase (GST) inhibitor with IC50s of 1.55 μM (sjGST) and 2.02 μM (hGSTM2), respectively. | ||
| M2557 | Ezatiostat | Apoptosis |
| TER199, TLK199 | ||
| Ezatiostat (TER199, TLK199) is a glutathione analog inhibitor of glutathione S-transferase (GST) P1-1. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. | ||
| M6747 | GGsTop | Others |
| Nahlsgen | ||
| GGsTop is a highly selective and irreversible inhibitor of γ-glutamyl transpeptidase (GGT), with a Ki of 170 μM for Human GGT. | ||
| M14445 | GSTO-IN-2 | Others |
| GSTO-IN-2 is a glutathione S-transferase inhibitor with IC50s of 3.6, 16.3, and 1.4 μM for GSTA2, GSTM1, and GSTP1-1. | ||
| M14494 | Sodium metatungstate | Pyroptosis |
| Sodium polyoxotungstate; POM-1 | ||
| Sodium metatungstate (Sodium polyoxotungstate) is a potent ecto-nucleoside triphosphate diphosphohydrolase (ENTPDase) inhibitor, with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1 (CD39), NTPDase 3 and NTPDase 2 respectively. | ||
| M21034 | SKI-V | SPHK |
| SKI V is a noncompetitive and potent inhibitor of non-lipid sphingosine kinase with IC50 of 2 μM for GST-hSK. SKI-V also inhibits PI3K with IC50 of 6 μM for hPI3k. SKI-V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P) and induces apoptosis with antitumor activity. | ||
| M22462 | Recombinant Human UBE2D1 (E.coli, N-GST) | Cytokines and Growth Factors |
| Ubiquitin-conjugating Enzyme E2 D1 | ||
| Recombinant Human UBE2D1 is produced by E.coli expression system and the target gene encoding Met1-Met147 is expressed with a GST tag at the N-terminus. Ubiquitin-conjugating enzyme E2 D1（UBE2D1）belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. | ||
| M22463 | Recombinant Human UBA1 Protein (Baculovirus-Insect, His & GST Tag) | Cytokines and Growth Factors |
| Ubiquitin Activating Enzyme E1 | ||
| The recombinant human UBA1/GST chimera consists of 1294 amino acids and has a calculated molecular mass of 146 KDa. A DNA sequence encoding the human UBA1 (NP_003325.2) (Ser 2-Arg 1058) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. | ||
| M29537 | LAS17 | Transferase |
| LAS17 is a potent and selective tyrosine-directed irreversible inhibitor for glutathione S-Transferase Pi (GSTP1) . LAS17 inhibits GSTP1 activity with an IC50 of 0.5 µM. | ||
| M29783 | DS20362725 | Estrogen Receptor |
| DS20362725 is an estrogen-related receptor α (ERRα) agonist. DS20362725 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an IC50 value of 0.6 μM. DS20362725 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM). | ||
| M29784 | DS45500853 | Estrogen Receptor |
| DS45500853 is an estrogen-related receptor α (ERRα) agonist. DS45500853 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an IC50 value of 0.80 μM. DS45500853 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM). | ||
| M30612 | NBDHEX | Glutathione Peroxidase |
| NBDHEX is a potent glutathione S-transferase P1-1 (GSTP1-1) inhibitor. NBDHEX induces apoptosis of tumor cells. NBDHEX acts as an anticancer agent by inhibiting GSTs catalytic activity, avoiding inconvenience of the inhibitor extrusion from the cell by specific pumps and disrupting the interaction between the GSTP1-1 and key signaling effectors. NBDHEX can also act as late-phase autophagy inhibitor. | ||
| M31186 | 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane | Others |
| TIPDSiCl2 | ||
| 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane (TIPDSiCl2,) is a silylation reagent that can be used to protect the 3'- and 5'-hydroxyl functions of ribonucleosides, to analyze Watson-Crick and Hoogstein base pairing in nucleotides, and to form ribavirin chemical delivery system. In addition, 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is also a protecting group reagent for open-chain polyhydroxy compounds, which can be used to prepare cyclic bridging peptides. | ||
| M40919 | Recombinant Human GSTM2 Protein (E. coli, His Tag) | Cytokines and Growth Factors |
| Glutathione S-transferase Mu 2; GST class-mu 2 | ||
| Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. A DNA sequence encoding the native human GSTM2 (Met 1-Lys 218) was expressed, with a polyhistide tag at the N-terminus. | ||
| M45374 | Terreic acid | Senolytics |
| Terreic acid is a quinone epoxide antibiotic and a potent Btk inhibitor, blocking the interaction between PKC and the PH domain of Btk.T Terreic acid also acts on HMC-1 human mast cell lysates, inhibiting the binding of GST-BtkPH to PKC with an IC50 of approximately 100 μM. Terreic acid also acts on HMC-1 human mast cell lysates to inhibit the binding of GST-BtkPH to PKC, with an IC50 of approximately 100 μM. In addition, Terreic acid simultaneously reduces the percentage of senescent cells and SASP expression in cells exposed to stress stimuli. | ||
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