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GGsTop is a highly selective and irreversible inhibitor of γ-glutamyl transpeptidase (GGT), with a Ki of 170 μM for Human GGT. GGsTop suppresses oxidative stress by inhibiting GGT activation. GGsTop prevents ischemia/reperfusion-induced acute kidney injury in rats in vivo.
| Molecular Weight | 331.26 |
| Formula | C13H18NO7P |
| CAS Number | 926281-37-0 |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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