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1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

Cat. No. M31186

All AbMole products are for research use only, cannot be used for human consumption.

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane Structure
Synonym:

TIPDSiCl2

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Quality Control & Documentation
Biological Activity

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane (TIPDSiCl2,) is a silylation reagent that can be used to protect the 3'- and 5'-hydroxyl functions of ribonucleosides, to analyze Watson-Crick and Hoogstein base pairing in nucleotides, and to form ribavirin chemical delivery system. In addition, 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is also a protecting group reagent for open-chain polyhydroxy compounds, which can be used to prepare cyclic bridging peptides.

Chemical Information
Molecular Weight 315.43
Formula C12H28Cl2OSi2
CAS Number 69304-37-6
Form Oil
Storage 2-8°C
References

[1] Daniel Kortus, et al. J Org Chem. Chemistry of 2,14-Dithiacalix[4]arene: Searching for the Missing Fifth Conformer

[2] Fumitaka Narumi, et al. Org Biomol Chem. Stereoselective dialkylation of the proximal hydroxy groups of calix- and thiacalix[4]arenes

[3] E Biała, et al. Acta Biochim Pol. Z-RNA. The synthesis of 2'-O-[13C]methyl- and 5-methyl-analogs of ribo-CGCGCG

[4] A Matsuda, et al. Carbohydr Res. Synthesis of 3-methylpseudouridine and 2'-deoxy-3-methyl-pseudouridine

[5] A Rosowsky, et al. J Med Chem. Improved synthesis of 2'-deoxyformycin A and studies of its in vitro activity against mouse lymphoma of T-cell origin

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Keywords: 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane, TIPDSiCl2 supplier, inhibitors, activators

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