Free shipping on all orders over $ 500

Terreic acid

Cat. No. M45374

All AbMole products are for research use only, cannot be used for human consumption.

Terreic acid Structure
Size Price Availability
1mg USD 328  USD328 3-4 Weeks
5mg USD 820  USD820 3-4 Weeks
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Terreic acid is a quinone epoxide antibiotic and a potent Btk inhibitor, blocking the interaction between PKC and the PH domain of Btk.T Terreic acid also acts on HMC-1 human mast cell lysates, inhibiting the binding of GST-BtkPH to PKC with an IC50 of approximately 100 μM. Terreic acid also acts on HMC-1 human mast cell lysates to inhibit the binding of GST-BtkPH to PKC, with an IC50 of approximately 100 μM. In addition, Terreic acid simultaneously reduces the percentage of senescent cells and SASP expression in cells exposed to stress stimuli.

Chemical Information
Molecular Weight 154.12
Formula C7H6O4
CAS Number 121-40-4
Form Solid
Storage -20°C, protect from light
References

[1] Chuixing Kong, et al. Sci Rep. Heterologous pathway assembly reveals molecular steps of fungal terreic acid biosynthesis

[2] Rashmi Sharma, et al. J Biomol Screen. Escherichia coli N-Acetylglucosamine-1-Phosphate-Uridyltransferase/Glucosamine-1-Phosphate-Acetyltransferase (GlmU) Inhibitory Activity of Terreic Acid Isolated from Aspergillus terreus

[3] Sanne H Olesen, et al. J Basic Microbiol. Differential antibacterial properties of the MurA inhibitors terreic acid and fosfomycin

[4] Huijong Han, et al. Biochemistry. The fungal product terreic acid is a covalent inhibitor of the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA)

[5] Y Kawakami, et al. Proc Natl Acad Sci U S A. Terreic acid, a quinone epoxide inhibitor of Bruton's tyrosine kinase

Related Senolytics Products
FOXO4-DRI acetate

FOXO4-DRI acetate is a cell-permeable peptide antagonist that blocks the interaction between FOXO4 and p53.FOXO4-DRI is an anti-aging peptide that induces apoptosis in senescent cells.

β-Galactosidase

β-Galactosidase is a glycoside hydrolase that hydrolyzes the β-glycosidic bond formed between galactose and its organic part. In Escherichia coli, the lacZ gene is the structural gene for β-galactosidase and can be used as part of the lac manipulator of the inducible system. β-Galactosidase hydrolyzes lactose to form glucose and galactose, which enter glycolysis, and also catalyzes the transgalactosylation of lactose to isolactose, which can be cleaved to monosaccharides.

Quercetin

Quercetin is a PI3K inhibitor with IC50 of 2.4-5.4 μM that has been shown to cause potent reversible inhibition of fatty-acid synthase.

Quercetin (>99%)

Quercetin is a PI3K inhibitor with IC50 of 2.4-5.4 μM that has been shown to cause potent reversible inhibition of fatty-acid synthase.

  Catalog
Abmole Inhibitor Catalog




Keywords: Terreic acid supplier, Senolytics, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.