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Senolytics Senolytics

Cat.No.  Name Information
M11068 Quercetin Quercetin is a PI3K inhibitor with IC50 of 2.4-5.4 μM that has been shown to cause potent reversible inhibition of fatty-acid synthase.
M3902 Quercetin (>99%) Quercetin is a PI3K inhibitor with IC50 of 2.4-5.4 μM that has been shown to cause potent reversible inhibition of fatty-acid synthase.
M45374 Terreic acid Terreic acid is a quinone epoxide antibiotic and a potent Btk inhibitor, blocking the interaction between PKC and the PH domain of Btk.T Terreic acid also acts on HMC-1 human mast cell lysates, inhibiting the binding of GST-BtkPH to PKC with an IC50 of approximately 100 μM. Terreic acid also acts on HMC-1 human mast cell lysates to inhibit the binding of GST-BtkPH to PKC, with an IC50 of approximately 100 μM. In addition, Terreic acid simultaneously reduces the percentage of senescent cells and SASP expression in cells exposed to stress stimuli.
M45370 FOXO4-DRI acetate FOXO4-DRI acetate is a cell-permeable peptide antagonist that blocks the interaction between FOXO4 and p53.FOXO4-DRI is an anti-aging peptide that induces apoptosis in senescent cells.
M45369 β-Galactosidase β-Galactosidase is a glycoside hydrolase that hydrolyzes the β-glycosidic bond formed between galactose and its organic part. In Escherichia coli, the lacZ gene is the structural gene for β-galactosidase and can be used as part of the lac manipulator of the inducible system. β-Galactosidase hydrolyzes lactose to form glucose and galactose, which enter glycolysis, and also catalyzes the transgalactosylation of lactose to isolactose, which can be cleaved to monosaccharides.




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