About 30 results found for searched term "Flavone" (0.03 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2079 | Chrysin | Cytochrome P450 (e.g. CYP17) |
| 5,7-Dihydroxyflavone | ||
| Chrysin is a naturally occurring flavone chemically extracted from the passion flowers Passiflora caerulea. | ||
| M3938 | Baicalin | GABA Receptor |
| Baicalein 7-O-β-D-glucuronide; 5, 6-dihydroxy-7-O-glucuronide flavone | ||
| Baicalin is an allosteric carnitine palmityl transferase 1 (CPT1) activator. Baicalin reduces the expression of NF-κB. | ||
| M4524 | Ligustroflavone | Calcium-sensing Receptor |
| Ligustroflavone, which can be extracted from Ligustrum lucidum, is a potential calcium sensitive receptor (CaSR) antagonist. Ligustroflavone has protective effect on diabetic osteoporosis mice. | ||
| M4540 | Scutellarein | Src-bcr-Abl |
| 6-Hydroxyapigenin; 4',5,6,7-Tetrahydroxyflavone | ||
| Scutellarein is a natural flavonoid with anti-inflammatory effects. | ||
| M4584 | Acacetin | Potassium Channel |
| 5,7-Dihydroxy-4'-methoxyflavone | ||
| Acacetin is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects. | ||
| M4589 | Luteolin | Keap1-Nrf2 |
| Luteolol; Digitoflavone; Flacitran; Luteoline | ||
| Luteolin (Luteolol) is a natural flavonoid that is a modulator of Nrf2. Luteolin exhibits dual regulation of Nrf2. In tumour cells, low concentrations of Luteolin activate the Nrf2 signalling pathway and promote Nrf2 nuclear translocation, while high concentrations of Luteolin inhibit Nrf2 activity and negatively modulate the Nrf2/ARE signalling pathway. Luteolin is also a PDE inhibitor. In addition, Luteolin has a variety of biological activities, including antioxidant, anti-inflammatory, anticancer, and neuroprotection. Luteolin can be used in studies related to ferroptosis. | ||
| M4699 | Galangin | Cytochrome P450 (e.g. CYP17) |
| 3,5,7-Trihydroxyflavone; Norizalpinin | ||
| Galangin (Norizalpinin) is a regulator of arylhydrocarbon receptors and also inhibits the activity of CYP1A1. | ||
| M4722 | Amentoflavone | Cytochrome P450 (e.g. CYP17) |
| Didemethyl-ginkgetin | ||
| Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone is a natural biflavone compound which has anti-inflammatory, antioxidative and neuroprotective effects. | ||
| M5304 | 7,8-Dihydroxyflavone | Trk |
| 7,8-DHF | ||
| 7,8-Dihydroxyflavone acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF). | ||
| M5547 | Daidzein | PARP |
| Isoflavone | ||
| Daidzein is an inactive analogue of genistein, a tyrosine kinase inhibitor and an estrogen receptor activator. | ||
| M6098 | Baicalein | Others |
| 5,6,7-Trihydroxyflavone | ||
| Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. | ||
| M7506 | 5-methoxyflavone | DNA/RNA Synthesis |
| 5-MF | ||
| 5-methoxyflavone is a novel DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. | ||
| M6451 | Apigenin | Cytochrome P450 (e.g. CYP17) |
| 4',5,7-Trihydroxyflavone; Apigenine; Apigenol; C.I. Natural Yellow 1 | ||
| Apigenin is a competitive CYP2C9 inhibitor with a Ki of 2 μM. | ||
| M8806 | 6, 2′, 4′-trimethoxyflavone | Others |
| 6, 2′, 4′-trimethoxyflavone is a selective aryl hydrocarbon receptor (AHR) antagonist with no partial agonist activity. | ||
| M9828 | 2-D08 | E1/E2/E3 Enzyme |
| 2D08; 2',3',4'-trihydroxyflavone | ||
| 2-D08 is a cell permeable, mechanistically unique inhibitor of protein SUMOylation. 2-D08 also inhibits Axl with an IC50 of 0.49 nM. | ||
| M9942 | Pratensein | Others |
| 5,7,3'-Trihydroxy-4'-methoxyisoflavone | ||
| Pratensein | ||
| M9944 | 7,4'-Dihydroxyflavone | CCR |
| 7,4'-Dihydroxyflavone, a flavonoid isolated from Glycyrrhiza uralensis, is an eotaxin/CCL11 inhibitor. | ||
| M10057 | α-Naphthoflavone | Cytochrome P450 (e.g. CYP17) |
| Alpha-Naphthoflavone; αNF | ||
| α-Naphthoflavone is a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis. | ||
| M10578 | Flavone | Metabolite/Endogenous Metabolite |
| 2-Phenyl-4-chromone | ||
| Flavone is an endogenous metabolite. | ||
| M10976 | Moslosooflavone | ROS |
| Moslosooflavoneone is a flavonoid isolated from snow lotus. Moslofoflavone has anti-hypoxic and anti-inflammatory activities. | ||
| M11075 | Scutellarein tetramethyl ether | Antibiotic |
| 4',5,6,7-Tetramethoxyflavone | ||
| Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive ingredient found in Siamese grass extract. Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) exerts anti-inflammatory activity through the NF-κB pathway. Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) modulates bacterial resistance through outflow pump inhibition. | ||
| M11109 | 3-O-Methylquercetin | PDE |
| 3',4',5,7-tetrahydroxy-3-methoxyflavone | ||
| 3-O-Methylquercetin (3-MQ), a main constituent of Rhamnus nakaharai, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis. 3-O-Methylquercetin (3-MQ) exhibits IC50 values of 31.9 μM， 86.9 μM， 18.6 μM and 1.6 μM for PDE1, PDE5, PDE2 and PDE4, respectively. | ||
| M13450 | 3',4',5',5,7-Pentamethoxyflavone | Others |
| 3',4',5',5, 7-pentamethoxyflavone is a natural brass compound extracted from Rutaceae. | ||
| M13514 | Neobavaisoflavone | Apoptosis |
| Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. | ||
| M13805 | 7-Methoxyisoflavone | AMPK |
| 7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK). | ||
| M14718 | Ipriflavone | Others |
| Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption. | ||
| M14960 | 5-Methyl-7-methoxyisoflavone | Cytochrome P450 (e.g. CYP17) |
| 5-Methyl-7-methoxyisoflavone is a sensational, non-steroidal anabolic isoflavone. 5-Methyl-7-methoxyisoflavone shows potency increasing muscle mass and endurance. 5-Methyl-7-methoxyisoflavone inhibits the enzyme aromatase, interfering with the normal metabolic pathways of testosterone. 5-Methyl-7-methoxyisoflavone is also an inhibitor for NF-κB. | ||
| M16546 | 2',4',5'-Trimethoxy-2'',2''- dimethylpyrano[5'',6'':6,7]isoflavone | Flavonoids |
| 2',4',5'-Trimethoxy-2'',2''- dimethylpyrano[5'',6'':6,7]isoflavone | ||
| M16548 | 3,5,8,3',4',5'-Hexamethoxy-6,7- methylenedioxyflavone | Flavonoids |
| 3,5,8,3',4',5'-Hexamethoxy-6,7- methylenedioxyflavone | ||
| M16550 | 5,8,4'-Trihydroxy-7-methoxyflavone 8-O-glucoside | Flavonoids |
| 5,8,4'-Trihydroxy-7-methoxyflavone 8-O-glucoside | ||
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