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Acacetin

Cat. No. M4584

All AbMole products are for research use only, cannot be used for human consumption.

Acacetin Structure
Synonym:

5,7-Dihydroxy-4'-methoxyflavone

Size Price Availability Quantity
1mg USD 20  USD20 In stock
5mg USD 35  USD35 In stock
10mg USD 55  USD55 In stock
25mg USD 95  USD95 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Acacetin is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects. Acacetin significantly reduces the Aβ levels by interfering with human APP proteolytic processing and BACE-1 expression. Acacetin inhibited the generation of the APP-CTF by affecting APP cleavage.

Chemical Information
Molecular Weight 284.26
Formula C16H12O5
CAS Number 480-44-4
Solubility (25°C) DMSO: ≥ 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Guangtao Zhang, et al. Acacetin inhibits invasion, migration and TGF-β1-induced EMT of gastric cancer cells through the PI3K/Akt/Snail pathway

[2] Chong Liu, et al. Acacetin Protects Myocardial Cells against Hypoxia-Reoxygenation Injury through Activation of Autophagy

[3] Yao Wu, et al. Acacetin exerts antioxidant potential against atherosclerosis through Nrf2 pathway in apoE -/- Mice

[4] Jos M Di Diego, et al. Acacetin suppresses the electrocardiographic and arrhythmic manifestations of the J wave syndromes

[5] Shilpi Singh, et al. Acacetin, a flavone with diverse therapeutic potential in cancer, inflammation, infections and other metabolic disorders

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Keywords: Acacetin, 5,7-Dihydroxy-4'-methoxyflavone supplier, Potassium Channel, inhibitors, activators

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