About 26 results found for searched term "AI-3" (0.068 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3640 | BAY 57-1293 | Anti-infection |
| Pritelivir; AIC316 | ||
| BAY 57-1293 is a potent helicase primase inhibitor that exhibites antiviral effect on herpes simplex virus (HSV) with IC50 of 20 nM for both HSV-1 and HSV-2. | ||
| M3787 | PAI-039 | PAI-1 |
| Tiplaxtinin | ||
| PAI-039 is an inhibitor of plasminogen activator inhibitor-1 (PAI-1). | ||
| M1622 | Secukinumab | IL Receptor/Related |
| AIN457; CAS# 1229022-83-6 | ||
| Secukinumab (AIN457) is a high-affinity monoclonal antibody against interleukin (IL-17A). Secukinumab (AIN457) is the first-in-class anti-IL-17 agent to be used in studies of plaque psoriasis, ankylosing spondylitis, and psoriatic arthritis. | ||
| M4152 | Daidzin | Dehydrogenase |
| Daidzoside; NPI-031D; Daidzein 7-O-glucoside | ||
| Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone. | ||
| M5899 | Procaine | Animal experimental anesthetics |
| Novocaine, Vitamin H3, Duracaine, Spinocaine | ||
| Procaine is a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M6418 | AI-3 | Others |
| AI-3 is a aRE activator; induces Nrf2-ARE-dependent transcription. | ||
| M10490 | Delcasertib | PKC |
| KAI-9803; BMS-875944 | ||
| Delcasertib (KAI-9803) is a potent and selective δ-protein kinase C (δPKC) inhibitor, it could ameliorate injury associated with ischemia and reperfusion in animal models of acute myocardial infarction (MI). | ||
| M13628 | EOAI3402143 | Deubiquitinase |
| EOAI3402143 is a deubiquitinase (DUB) inhibitor, which inhibits dose-dependently inhibits Usp9x/Usp24 and Usp5. | ||
| M13858 | Delcasertib hydrochloride | PKC |
| KAI-9803 hydrochloride; BMS-875944 hydrochloride | ||
| Delcasertib (KAI-9803) hydrochloride is a potent and selective δ-protein kinase C (δPKC) inhibitor. | ||
| M14735 | NAI-N3 | Others |
| NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment). | ||
| M17706 | 6″-O-Acetylsaikosaponin b3 | Triterpenoids |
| 6″-O-Acetylsaikosaponin b3 | ||
| M17764 | Saikosaponin b3 | Triterpenoids |
| Saikosaponin b3 | ||
| M20465 | Diaveridine | Others |
| AI3-23935, CCRIS-3784 | ||
| Diaveridine is coccidiostat with anti-parasitic activity and also a dihydrofolate reductase (DHFR) inhibitor preventing folic acid synthesis in species of Pneumocystis. | ||
| M21571 | Recombinant Human CD3E (Mammalian, C-mFc) | Recombinant Proteins |
| T-Cell Surface Glycoprotein CD3 Epsilon Chain; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain | ||
| The recombinant human t cell surface glycoprotein CD3 Epsilon chain is produced by mammalian expression systems, and the target gene encoding Gln22-Thr48 is expressed at the C-terminal using mouse IgG1 Fc tag. Protein number: P07766. | ||
| M21572 | Recombinant Human CD3E (Mammalian, C-Fc) | Recombinant Proteins |
| T-Cell Surface Glycoprotein CD3 Epsilon Chain; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain | ||
| Recombinant human t cell surface glycoprotein CD3 Epsilon chain is produced by mammalian expression system, and the target gene encoding Asp23-Asp126 is expressed in the C-terminal human IgG1 Fc tag. Protein number: P07766. | ||
| M28405 | Pritelivir mesylate hydrate | Anti-infection |
| AIC316 mesylate hydrate; BAY 57-1293 mesylate hydrate | ||
| Pritelivir mesylate hydrate (BAY 57-1293 mesylate hydrate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate hydrate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2. | ||
| M28406 | Pritelivir mesylate | Anti-infection |
| AIC316 mesylate; BAY 57-1293 mesylate | ||
| Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2. | ||
| M41661 | BET bromodomain inhibitor 3 | Epigenetic Reader Domain |
| BET bromodomain inhibitor 3 is BET bromodomain inhibitor. | ||
| M45372 | NLRP3/AIM2-IN-3 | NLR |
| NLRP3/AIM2-IN-3 is a potent inhibitor that interferes with the interaction of NLRP3 or AIM2 with the bridging protein ASC and inhibits ASC oligomerization, and has different species-specific effects on NLRP3 and AIM2 inflammasome-dependent pyroptosis. In addition, NLRP3/AIM2-IN-3 inhibited LPS/nigericin-stimulated cell pyroptosis in THP-1 macrophages with an IC50 of 0.077 ± 0.008 μM. | ||
| M51190 | Insulin alpha-chain (1-13) | Others |
| Insulin alpha-chain (1-13) is a human leucocyte antigen (HLA)-DR4-restricted epitope comprising the first 13 amino acids of the insulin A-chain. | ||
| M51613 | Fibrinogen γ-chain (397-411) | Others |
| Fibrinogen γ-chain (397-411), a esidues 397-411 of the γ chain of fibrinogen, is a site recognizing the platelet receptor, which is distinct from the site(s) involved in polymerization of fibrin monomers. | ||
| M53272 | Brain Natriuretic Peptide (1-32), rat | Angiotensin Receptor |
| Brain Natriuretic Peptide (1-32), rat (BNP (1-32), rat) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). | ||
| M53453 | Influenza A NP(366-374) Strain A/PR/8/35 | Anti-infection |
| Influenza A NP(366-374) Strain A/PR/8/35 is an H2-Db-restricted epitope from Influenza A/PR/8/35 nucleoprotein. | ||
| M54061 | [cPP1-7, NPY19-23, Ala31, Aib32, Gln34]-hPancreatic Polypeptide | Neuropeptide Receptor |
| [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. | ||
| M54496 | Insulin β Chain Peptide (15-23) | Others |
| Insulin β Chain Peptide (15-23), also known as INS, is an insulin-derived peptide recognized by islet-associated T cells. | ||
| M54811 | Recombinant Dengue virus (DENV) (type 2, strain New Guinea C) NS1 Protein (HEK293, N-His) | Recombinant Proteins |
| DENV-NS1 Protein | ||
| The Recombinant Dengue virus (type 2, strain New Guinea C) NS1 consists of 371 amino acids and predicts a molecular mass of 42.3 kDa. A DNA sequence encoding the Dengue virus (type 2, strain New Guinea C) NS1 (Asp1-Ala352) was expressed with a polyhistidine tag at the N-terminus. | ||
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