| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M21511 | RGLS4326 | RGLS4326 (RG4326) is a first-in-class microRNA-17 (miR-17) oligonucleotide inhibitor. RGLS4326 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD). RGLS4326 acts on HeLa cells to inhibit the function of miR-17 with EC50 value of 28.3 nM. |
| M21499 | Rodatristat ethyl | Rodatristat ethyl (KAR5585) was a first-in-class inhibitor of tryptophan hydroxylase 1 (TPH1) with oral activity. |
| M21497 | Gemcabene calcium | Gemcabene calcium (PD-72953 calcium), the pioneering (first-in-class) lipid-lowering agent, can lower density lipoprotein cholesterol (LDL-C), lower triglycerides, and increase high-density lipoprotein cholesterol (HDL-C), and lower pro-inflammatory acute phase proteins. C-reactive protein (CRP), which shows anti-inflammatory activity. |
| M21473 | Padsevonil | Padsevonil (UCB0942) is the first effective antiepileptic agent. Padsevonil can be used in the study of epilepsy. |
| M21472 | Gemcabene | Gemcabene (PD-72953) is a first-in-class PPARα agonist, lipid-lowering agent. It lowers density lipoprotein cholesterol (LDL-C), lowers triglycerides and increases high density lipoprotein cholesterol (HDL-C), and lowers the pro-inflammatory acute phase protein, C-reactive protein (CRP), showing anti-inflammatory activity. |
| M21462 | 24-Norursodeoxycholic acid | 24 norursodeoxycholic acid (nor UDCA) is a C23 homologue of UDCA with shortened side chain, which has effective anti cholestasis, anti-inflammatory and anti fibrosis properties. |
| M21454 | Cyclohexanecarboxamide | Cyclohexanecarboxamide is a useful chemical for research. |
| M21439 | Poly-D-lysine hydrobromide (70,000-150,000) | Poly-D-lysine hydrobromide (70,000-150,000) |
| M21432 | Hyaluronic Acid (10K) | Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. |
| M21361 | Tetramethyluric Acid | Tetramethyluric Acid is a purine alkaloid found in the leaves of wild bitter tea (Camellia kucha Hung T. Chang) with a molecular structure that has one more methyl group than the caffeine commonly found in tea leaves. |
| M21351 | 2-Benzylsuccinic acid | 2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is a potent inhibitor of carboxypeptidase A (CPA). |
| M21339 | 2-(Chloromethyl)benzoic acid | 2-Chloromethylbenzoic Acid acts as a reagent for the synthesis of (azolyl)methyl)arylbenzamides as dual inhibitors of VEGFR-1/2 kinases. |
| M21333 | 11-Mercaptoundecanoic acid | 11-Mercaptoundecanoic acid (MUA), a thiol-containing fatty acid used to design monolayers, has been used to prepare self-assembled monolayers (SAMs), hybrid monolayers, and metal-conjugated nanoparticles. |
| M21208 | BCATc Inhibitor 2 | BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 µM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 µM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration. |
| M21152 | SJ6986 | SJ6986 is a potent, selective, and orally effective GSPT1/2 degradation agent with a DC50 value of 2.1 nM (Dmax 99%) for GSPT1. |
| M21133 | VT107 | The pan-TEAD transcription factor inhibitor VT-104 binds to a lipid pocket on TEAD, preventing its auto-palmitoylation, similar to the previously highlighted TEAD inhibitors. |
| M21103 | Iclepertin | Iclepertin (BI 425809) is an oral glycine transporter-1 (GlyT1) inhibitor being developed for the study of cognitive impairment associated with schizophrenia (CIAS). |
| M21077 | BMS-986176 | BMS-986176/LX-9211 is an orally administered, CNS-penetrating AAK1 kinase inhibitor with an IC50 of 2 nM that is being developed for use in neuropathic pain studies. |
| M21073 | 4-Deoxypyridoxine hydrochloride | 4-Deoxypyridoxine hydrochloride is a vitamin B6 antimetabolite with diverse biological activities. |
| M21046 | Bakkenolide A | Bakkenolide A, extracted from Petasites tricholobus, has been suggested to against cancer and display protective effects on inflammatory cytokines formation. |
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