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Diethyl pyrocarbonate 

Cat. No. M31254

All AbMole products are for research use only, cannot be used for human consumption.

Diethyl pyrocarbonate  Structure
Size Price Availability Quantity
100mg USD 48  USD48 In stock
250mg USD 65  USD65 In stock
500mg USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Diethyl pyrocarbonate is a potent, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues.

Chemical Information
Molecular Weight 162.14
Formula C6H10O5
CAS Number 1609-47-8
Form Liquid
Solubility (25°C) DMSO 90 mg/mL
Storage -20°C, sealed
References

[1] K N Dzhandzhugazyan, et al. Biochim Biophys Acta. Diethyl pyrocarbonate inactivates CD39/ecto-ATPDase by modifying His-59

[2] D C Lu, et al. Respir Physiol. Diethyl pyrocarbonate (DEPC) inhibits CO2 chemosensitivity in Helix aspersa

[3] P M Scholten, et al. Nucleic Acids Res. Diethyl pyrocarbonate: a chemical probe for DNA cruciforms

[4] I Fedorcsák, et al. Biochem Biophys Res Commun. Diethyl pyrocarbonate does not degrade RNA

[5] L Ehrenberg, et al. Prog Nucleic Acid Res Mol Biol. Diethyl pyrocarbonate in nucleic acid research

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Keywords: Diethyl pyrocarbonate  supplier, inhibitors, activators

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