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Methyl linolenate

Cat. No. M31153
Methyl linolenate Structure
Synonym:

Linolenic acid methyl ester

Size Price Availability Quantity
100mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Methyl linolenate is a fatty acid methyl ester derived from α-linolenic acid, which is also an insect attractant. In addition, Methyl linolenate can inhibit the oxidation of unsaturated fatty acid methyl esters with an IC50 of 60 μM.

Chemical Information
Molecular Weight 292.46
Formula C19H32O2
CAS Number 301-00-8
Form Liquid
Storage -20°C
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Gyeong-A Ko, et al. Nutr Res Pract. Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway

[2] H W Chan, et al. Lipids. Autoxidation of methyl linolenate: Analysis of methyl hydroxylinolenate isomers by high performance liquid chromatography

[3] Rosario Zamora, et al. J Agric Food Chem. Comparative methyl linoleate and methyl linolenate oxidation in the presence of bovine serum albumin at several lipid/protein ratios

[4] E N Frankel, et al. Basic Life Sci. Thermal decomposition of methyl linoleate and methyl linolenate hydroperoxides analyzed by capillary gas chromatography

[5] R Kumarathasan, et al. Prog Lipid Res. Autoxidation and yellowing of methyl linolenate

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Keywords: Methyl linolenate, Linolenic acid methyl ester supplier, inhibitors, activators


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