| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M21208 | BCATc Inhibitor 2 | BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 µM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 µM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration. |
| M21152 | SJ6986 | SJ6986 is a potent, selective, and orally effective GSPT1/2 degradation agent with a DC50 value of 2.1 nM (Dmax 99%) for GSPT1. |
| M21133 | VT107 | The pan-TEAD transcription factor inhibitor VT-104 binds to a lipid pocket on TEAD, preventing its auto-palmitoylation, similar to the previously highlighted TEAD inhibitors. |
| M21103 | Iclepertin | Iclepertin (BI 425809) is an oral glycine transporter-1 (GlyT1) inhibitor being developed for the study of cognitive impairment associated with schizophrenia (CIAS). |
| M21077 | BMS-986176 | BMS-986176/LX-9211 is an orally administered, CNS-penetrating AAK1 kinase inhibitor with an IC50 of 2 nM that is being developed for use in neuropathic pain studies. |
| M21073 | 4-Deoxypyridoxine hydrochloride | 4-Deoxypyridoxine hydrochloride is a vitamin B6 antimetabolite with diverse biological activities. |
| M21046 | Bakkenolide A | Bakkenolide A, extracted from Petasites tricholobus, has been suggested to against cancer and display protective effects on inflammatory cytokines formation. |
| M21044 | DL-Serine | DL-Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV). |
| M21017 | Sugammadex sodium | Sugammadex sodium is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery in adults. |
| M21010 | L-Carnosine | L-Carnosine is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress. |
| M21009 | L-Ornithine hydrochloride | L-ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle. |
| M21007 | Phytic acid | Phytic acid is the principal storage form of phosphorus in many plant tissues, especially bran and seeds. It can act as a cofactor in DNA repair by nonhomologous end-joining. |
| M21005 | Dipivefrin Hydrochloride | Dipivefrin (Dipivefrine, Propine, Pivalephrine) is a prodrug of epinephrine which is hydrolyzed to epinephrine after absorption into the eye. |
| M20962 | Uridine triacetate | Uridine triacetate is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity. |
| M20955 | BT-11 | BT-11 is an orally active lanthionine synthetase C-like 2 (LANCL2) binding compound for treating inflammatory bowel disease (IBD) (Kd value of 7.7 µM). |
| M20912 | Ropivacaine Mesilate | Ropivacaine Mesilate is the mesylate form of ropivacaine, which is a member of the amino amide class of local anesthetics. |
| M20901 | Piperonyl butoxide | Piperonyl butoxide (PBO) is a man-made pesticide synergist, working with insect killers to increase their effectiveness. |
| M20893 | Tyramine | Tyramine is a naturally occurring trace amine derived from the amino acid tyrosine and acts as a catecholamine releasing agent. |
| M20891 | Grape Seed Extract | Grape Seed Extract are industrial derivatives from whole grape seeds that have a great concentration of vitamin E, flavonoids, linoleic acid, and OPCs. |
| M20855 | Guanethidine Monosulfate | Guanethidine monosulfate is an antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. |
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