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Relatlimab

Cat. No. M24782

All AbMole products are for research use only, cannot be used for human consumption.

Relatlimab Structure
Synonym:

BMS-986016

Size Price Availability Quantity
100ug USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC50 value of 0.019 nM. Relatlimab can be used in research of cancer.

Chemical Information
CAS Number 1673516-98-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Lewis Au, et al. Cell. Relatlimab and nivolumab in the treatment of melanoma

[2] Rodabe N Amaria, et al. Nature. Neoadjuvant relatlimab and nivolumab in resectable melanoma

[3] Kent Thudium, et al. Cancer Immunol Res. Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab

[4] Julia Paik. Drugs. Nivolumab Plus Relatlimab: First Approval

[5] Hussein A Tawbi, et al. N Engl J Med. Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma

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Keywords: Relatlimab, BMS-986016 supplier, inhibitors, activators

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