| Cat.No. | Name | Information |
|---|---|---|
| M2076 | SP600125 | SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM. |
| M21224 | CC-90001 | CC-90001 is a JNK (c-Jun N-terminal kinase) inhibitor that can be used as a Phase II clinical candidate to study idiopathic pulmonary fibrosis. |
| M14161 | SU3327 | SU3327 is a potent, selective and substrate-competitive JNK inhibitor with an IC50 of 0.7 μM. |
| M14159 | Juglanin | Juglanin, a natural occurring flavonoid, is a JNK acticator, with inflammation and anti-tumor activities. Juglanin can induce apoptosis and autophagy on human breast cancer cells. |
| M14158 | JNK-IN-7 | JNK-IN-7 is a potent JNK inhibitor with IC50 of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, respectively. |
| M14157 | D-JNKI-1 | D-JNKI-1 (AM-111) is a highly potent and cell-permeable peptide inhibitor of JNK. |
| M14156 | CC-401 hydrochloride | CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM. |
| M11008 | IQ-3 | IQ-3 is a specific inhibitor of the c-JNK family and is more selective for JNK3. IQ-3 for JNK1, JNK2, and JNK3 Kd The values are 0.24 μM, 0.29 μM, and 0.066 μM, respectively. |
| M10695 | WHI-P258 | WHI-P258 is an inhibitor of JAK3 with a Ki value of 72 μM. |
| M10633 | AS601245 | AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50 values of 150, 220, and 70 nM for JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. |
| M10365 | L-JNKI-1 | L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK. |
| M9718 | DB07268 | DB07268 is is a potent and selective JNK1 inhibitor, with IC50 of 9 nM. |
| M9388 | Tanzisertib | Tanzisertib (CC-930) is a potent JNK1/2/3 inhibitor with IC50s of 61/7/6 nM, respectively. |
| M9176 | DTP3 | DTP3 is a selective GADD45β/MKK7 inhibitor, which inhibits cancer-selective NF-κB survival pathway. |
| M9175 | Vacquinol-1 | Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death. |
| M8946 | IQ-1S | IQ-1S is a potent and selective JNK inhibitor with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively. |
| M8921 | Bentamapimod | Bentamapimod, also known as AS602801, is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively. |
| M7395 | TCS JNK 6o | TCS JNK 6o is a selective JNK inhibitor. |
| M6503 | BI 78D3 | BI 78D3 is a selective, competitive JNK inhibitor. |
| M5145 | Anisomycin | Anisomycin is a pyrrolidine antibiotic, which inhibits protein synthesis, and also act as a JNK activator. |
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