| Cat.No. | Name | Information |
|---|---|---|
| M2076 | SP600125 | SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM. |
| M4361 | Polyphyllin-I | Polyphyllin I is a bioactive ingredient extracted from Paris Polyphylla with strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis. |
| M4340 | Cinobufagin | Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans. |
| M2785 | JNK Inhibitor IX (SC202671) | JNK inhibitor IX is a selective and potent JNK inhibitor with pIC50 of 6.5 and 6.7 for JNK2 and JNK3, respectively. |
| M2013 | JNK-IN-8 | JNK-IN-8 is a selective JNK inhibitor that inhibits phosphorylation of c-Jun. |
| M52816 | JIP-1(153-163) | JIP-1(153-163) (TI-JIP) is a peptide inhibitor of c-JNK, based on residues 153-163 of JNK-interacting protein-1 (JIP-1) (Modifications: Phe-11 = C-terminal amide). |
| M49724 | JNK3 inhibitor-5 | JNK3 inhibitor-5 is a potent and selective JNK3 inhibitor with an IC50 of 0.379 nM. |
| M42128 | JNK-1-IN-1 | JNK-1-IN-1 is a JNK-1 inhibitor. |
| M42127 | JNK2-IN-1 | JNK2-IN-1 is a JNK2 inhibitor (Kds: 79.2 μM). |
| M42126 | JNK-1-IN-2 | JNK-1-IN-2 is a JNK-1 inhibitor (IC50: 33.5 nM). |
| M42125 | JNK3 inhibitor-6 | JNK3 inhibitor-6 is a selective JNK3 Inhibitor (IC50=78 nM). |
| M42124 | JNK3 inhibitor-7 | JNK3 inhibitor-7 is a potent, orally active and cross the blood-brain barrier JNK3 inhibitor with IC50 values of 53, 973, 1039 nM for JNK3, JNK2, JNK1, respectively. |
| M42123 | JNK-IN-12 | JNK-IN-12 is a mitochondrial-targeted JNK inhibitor (IC50=66.3 nM), consisting of a mitochondrial-specific cell-penetrating peptide and a specific inhibitor of JNK, SP600125. |
| M42122 | JNK3 inhibitor-8 | JNK3 inhibitor-8 is a potent, delective, orally active and cross the blood-brain barrier JNK3 inhibitor with IC50 values of 21, 2203, >10000 nM for JNK3, JNK2, JNK1, respectively. |
| M29643 | YL5084 | YL5084, a covalent JNK inhibitor, exhibits selectivity for JNK2 and JNK3 over JNK1 with IC50s of 70 nM, 84 nM and 2173 nM, respectively. YL5084 exhibits JNK2-independent antiproliferative effects and induces apoptosis in a JNK2-independent manner. |
| M27823 | SR-3306 | SR-3306 is a selective, potent, highly brain penetrant JNK inhibitor. |
| M21224 | CC-90001 | CC-90001 is a JNK (c-Jun N-terminal kinase) inhibitor that can be used as a Phase II clinical candidate to study idiopathic pulmonary fibrosis. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
