|M10159||Kaempferol 3-O-β-D-glucuronide||Kaempferol 3-O-β-D-glucuronide is a conjugated kaempferol metabolite, which has anti-inflammatory effect.|
|M10139||Anakinra||Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R.|
|M9868||GIBH-130||GIBH-130 is a neuroinflammation inhibitor, with IC50 value of 3.4 nM for suppressing the IL-1β secretion by activated microglia.|
|M6258||CA-4948||CA-4948 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades, and demonstrates pharmacodynamic and antitumor activity in in vitro and in vivo nonclinical models.|
|M3814||Sarilumab||Sarilumab is a human recombinant IgG1 antibody that binds to both forms of interleukin 6 receptors (IL-6R), thus inhibiting the IL-6-mediated signaling.|
|M2626||Dexamethasone Sodium Phosphate||Dexamethasone is an interleukin receptor inhibitor and also suppresses COX-2.|
|M1622||Secukinumab||Secukinumab is a human IgG1κ monoclonal antibody that binds to the protein interleukin (IL)-17A.|
|M1621||Ustekinumab||Ustekinumab is a human monoclonal antibody directed against interleukin 12 and interleukin 23, naturally occurring proteins that regulate the immune system and immune-mediated inflammatory disorders.|
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