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Taurohyodeoxycholic acid (THDCA) sodium prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurohyodeoxycholic acid sodium can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model.
| Molecular Weight | 521.69 |
| Formula | C26H44NNaO6S |
| CAS Number | 38411-85-7 |
| Solubility (25°C) | Water 35 mg/mL DMSO 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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