| Cat.No. | Name | Information |
|---|---|---|
| M6189 | Ossirene (AS101) | Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme. |
| M6223 | Tocilizumab | Tocilizumab is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD. |
| M10139 | Anakinra | Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. |
| M54551 | Rademikibart | Rademikibart is a human IgG4ҡ monoclonal antibody that targets IL-4 Rα to block inflammatory signaling induced by IL-4 and IL-13, two important cytokines that drive allergic inflammation, and binds to the human IL-4Rα epitope with a KD of 20.7 pM. Rademikibart does not bind to IL-4Rα from other species. Rademikibart does not bind to IL-4Rα of other species.Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation, and TARC production in PBMC, and can be used in studies related to moderate-to-severe Th2 inflammatory diseases. |
| M54550 | Stapokibart | Stapokibart is a humanized monoclonal antibody targeting IL-4Rα that blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit, IL-4Rα. Stapokibart is able to interact with IL-4Rα in humans, cynomolgus monkeys, and rats, and can be used in atopic dermatitis research. |
| M54371 | Erepdekinra | Erepdekinra is an interleukin-17A (IL-17A) receptor antagonist. |
| M54008 | AF12198 | AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 µM) or the murine type I receptor (IC50>200 µM). |
| M53841 | Ac-YVAD-CHO | Ac-YVAD-CHO (L-709049) is a potent, reversible, specific tetrapeptide interleukin-lβ converting enzyme (ICE) inhibitor with mouse and human Ki values of 3.0 and 0.76 nM. |
| M52856 | Antiflammin-1 | Antiflammin-1 is an anti-inflammatory peptide 1 (MQMKKVLDS). |
| M52855 | β-Interleukin II (44-56) | β-Interleukin II (44-56) is a 44-56 fragment of beta-interleukin II polypeptide. |
| M52854 | Interleukin II (60-70) | Interleukin II (60-70) is a 60-70 fragment of the cytokine Interleukin II polypeptide. |
| M52853 | Acetyl hexapeptide-49 | Acetyl hexapeptide-49 is a bioactive peptide with anti-allergen effect and has been reported used as a cosmetic ingredient. |
| M52852 | Myelopeptide-2 | Myelopeptide-2 is a peptide which can restore mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. |
| M52851 | Romurtide | Romurtide (Muroctasin), a synthetic muramyl dipeptide derivative, is a cytokines inducer. |
| M52850 | YVAD-CHO | YVAD-CHO is an interleukin-1β converting enzyme (ICE, caspase 1) inhibitor that can partially delay motoneurone death in lesioned facial nerve mice. |
| M52849 | Lib2-1 | Lib2-1, a macrocyclic peptide, is an IL-17C/IL-17RE interaction inhibitor. |
| M52817 | [D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P | [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P, a Substance P derivative, is a biased agonist toward neuropeptide and chemokine receptors. |
| M49645 | Balsalazide sodium hydrate | Balsalazide sodium hydrate could suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway. |
| M49465 | JNJ-77242113 | JNJ-77242113 is a synthetic peptide and also an orally active IL-23R inhibitor for studies related to plaque psoriasis. |
| M49455 | CALY-002 | CALY-002 is a potential best-in-class (BIC), humanized monoclonal antibody targeting IL-15 for studies related to immune diseases. |
| M49354 | Auremolimab | Auremolimab is an ultra-humanized monoclonal antibody against IL-2Rβ (CD122) that targets and depletes tissue-resident memory T-cells, and may be used in vitiligo-related studies. |
| M45367 | Genakumab | Genakumab is a monoclonal antibody targeting IL-1β that can be used in studies related to gout. |
| M45223 | Casdozokitug | Casdozokitug is an IgG1κ antibody targeting IL27. |
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