| Cat.No. | Name | Information |
|---|---|---|
| M6189 | Ossirene | Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta (IL-1β) converting enzyme. Ossirene abolishes phosphorylation of STAT3 by inhibiting IL-10. Ossirene also inhibits Caspase-1. |
| M6223 | Tocilizumab | Tocilizumab is a humanized monoclonal antibody that binds to the interleukin-6 receptor. Tocilizumab prevents binding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab can be used for the research of rheumatoid arthritis and COVID-19. |
| M10139 | Anakinra | Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. |
| M1622 | Secukinumab | Secukinumab (AIN457) is a high-affinity monoclonal antibody against interleukin (IL-17A). Secukinumab (AIN457) is the first-in-class anti-IL-17 agent to be used in studies of plaque psoriasis, ankylosing spondylitis, and psoriatic arthritis. |
| M2594 | Montelukast sodium | Montelukast sodium selectively antagonizes leukotriene D 4 (LTD4) by binding to it so that block the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1. |
| M2559 | VGX-1027 | VGX-1027 is an orally active immunomodulator. |
| M1621 | Ustekinumab | Ustekinumab is a human monoclonal antibody that targets IL12 and IL23, natural proteins that regulate the immune system and immune-mediated inflammatory diseases. |
| M59412 | RP-54745 | RP-54745 is an inhibitor of macrophage stimulation and interleukin-1 production, and a potential antirheumatic compound. |
| M59155 | RS17 | RS17 is an anti-tumor peptide designed to bind specifically to the CD47 molecule and block the interaction between CD47 and its ligand, SIRPα, on the surface membrane of macrophages. |
| M58640 | IL-17A modulator-2 | IL-17A modulator-2 is a IL-17A modulator. IL-17A modulator-2 inhibits the biological action of IL-17A with a pIC50 of 8.3. IL-17A modulator-2 can be used for the research of diseases associated with modulation of IL-17A activity. |
| M56367 | IL-15-IN-1 | IL-15-IN-1 is a potent and selective Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells with an IC50 of 0.8 μM. |
| M56366 | IL-17 modulator 3 | IL-17 modulator 3 is an IL-17 modulator. |
| M56364 | IL-17A modulator-3 | IL-17A modulator-3 is a IL-17A modulator. |
| M56363 | IL-17 modulator 4 sulfate | IL-17 modulator 4 sulfate is a proagent of IL-17 modulator 1. |
| M54690 | HB0017 | HB0017 is a monoclonal antibody that targets interleukin-17 (IL-17) and selectively binds IL-17A, thereby preventing IL-1717A from binding to its receptor. |
| M54550 | Stapokibart | Stapokibart is a humanized monoclonal antibody targeting IL-4Rα that blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit, IL-4Rα. Stapokibart is able to interact with IL-4Rα in humans, cynomolgus monkeys, and rats, and can be used in atopic dermatitis research. |
| M52856 | Antiflammin-1 | Antiflammin-1 is an anti-inflammatory peptide 1 (MQMKKVLDS). |
| M52855 | β-Interleukin II (44-56) | β-Interleukin II (44-56) is a 44-56 fragment of beta-interleukin II polypeptide. |
| M52854 | Interleukin II (60-70) | Interleukin II (60-70) is a 60-70 fragment of the cytokine Interleukin II polypeptide. |
| M52853 | Acetyl hexapeptide-49 | Acetyl hexapeptide-49 is a bioactive peptide with anti-allergen effect and has been reported used as a cosmetic ingredient. |
| M52852 | Myelopeptide-2 | Myelopeptide-2 is a peptide which can restore mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. |
| M52851 | Romurtide | Romurtide (Muroctasin), a synthetic muramyl dipeptide derivative, is a cytokines inducer. |
| M52850 | YVAD-CHO | YVAD-CHO is an interleukin-1β converting enzyme (ICE, caspase 1) inhibitor that can partially delay motoneurone death in lesioned facial nerve mice. |
| M52849 | Lib2-1 | Lib2-1, a macrocyclic peptide, is an IL-17C/IL-17RE interaction inhibitor. |
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