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Hydrocortisone sodium succinate

Cat. No. M20846

All AbMole products are for research use only, cannot be used for human consumption.

Hydrocortisone sodium succinate Structure
Synonym:

Hydrocortisone 21-hemisuccinate sodium salt

Size Price Availability Quantity
5mg USD 20  USD20 In stock
10mg USD 25  USD25 In stock
25mg USD 50  USD50 In stock
50mg USD 70  USD70 In stock
100mg USD 90  USD90 In stock
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Biological Activity

Hydrocortisone sodium succinate (Hydrocortisone 21-hemisuccinate sodium salt) has significant inhibitory effects on the IL-6 bioactivity with IC50 of 6.7 μM. Hydrocortisone sodium succinate can bind to glucocorticoid receptor, initiating the transcription of anti-inflammatory and immunosuppressive mediators.

Chemical Information
Molecular Weight 484.51
Formula C25H33O8.Na
CAS Number 125-04-2
Solubility (25°C) DMSO 97 mg/mL
Water 97 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Katja Mihovec, et al. Acta Chim Slov. Evaluation of the stability of hydrocortisone sodium succinate in solutions for parenteral use by a validated HPLC-UV method

[2] He Li, et al. Neurol Res. Effects of hydrocortisone sodium succinate on voltage-gated sodium current in trigeminal ganglion neurons of rat

[3] B A Feigenbaum, et al. J Allergy Clin Immunol. Hydrocortisone sodium succinate does not cross-react with aspirin in aspirin-sensitive patients with asthma

[4] D A Fulcher, et al. Med J Aust. Anaphylactoid reaction to intravenous hydrocortisone sodium succinate: a case report and literature review

[5] E Novak, et al. Clin Pharmacol Ther. Anorectal pruritus after intravenous hydrocortisone sodium succinate and sodium phosphate

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Keywords: Hydrocortisone sodium succinate, Hydrocortisone 21-hemisuccinate sodium salt supplier, IL Receptor/Related, inhibitors, activators

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