About 5 results found for searched term "125-04-2" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20846 | Hydrocortisone sodium succinate | IL Receptor/Related |
| Hydrocortisone 21-hemisuccinate sodium salt | ||
| Hydrocortisone sodium succinate (Hydrocortisone 21-hemisuccinate sodium salt) has significant inhibitory effects on the IL-6 bioactivity with IC50 of 6.7 μM. Hydrocortisone sodium succinate can bind to glucocorticoid receptor, initiating the transcription of anti-inflammatory and immunosuppressive mediators. | ||
| M28056 | MK-7145 | Potassium Channel |
| MK-7145 is a ROMK inhibitor, with an IC50 of 0.045 μM. | ||
| M28873 | LSP-249 | Serine/Threonine Protease |
| LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell. | ||
| M11415 | (Rac)-JBJ-04-125-02 | EGFR/HER2 |
| JBJ-04-125-02 racemate | ||
| (Rac)-JBJ-04-125-02 is a racemate of JBJ-04-125-02, which is a potent, selectively mutated, allosteric and oral active EGFR inhibitor. The IC50 of EGFRL858R/T790M was 0.26 nM. | ||
| M29151 | JBJ-04-125-02 | EGFR/HER2 |
| JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M. JBJ-04-125-02 can inhibit cancer cell proliferation and EGFRL858R/T790M/C797S signaling. JBJ-04-125-02 has anti-tumor activities. | ||
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