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Lebrikizumab

Cat. No. M25309

All AbMole products are for research use only, cannot be used for human consumption.

Lebrikizumab Structure
Synonym:

TNX-650

Size Price Availability Quantity
100ug USD 170  USD170 In stock
1mg USD 290  USD290 In stock
5mg USD 750  USD750 In stock
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Quality Control & Documentation
Biological Activity

Lebrikizumab is a humanized monoclonal antibody to IgG4κ that binds with high affinity and specificity to interleukin 13 (IL-13) and inhibits its function, thereby preventing the formation of the IL-13Rα1/IL-4Rα complex and inhibiting the signaling pathway mediated by this receptor complex.Lebrikizumab has been used in asthma and atopic dermatitis studies. Lebrikizumab may be used in asthma and atopic dermatitis studies.

Chemical Information
CAS Number 953400-68-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Jonathan I Silverberg, et al. N Engl J Med. Two Phase 3 Trials of Lebrikizumab for Moderate-to-Severe Atopic Dermatitis

[2] Angelina Labib, et al. Clin Cosmet Investig Dermatol. Managing Atopic Dermatitis with Lebrikizumab - The Evidence to Date

[3] Tiffany Y Loh, et al. J Asthma Allergy. Therapeutic Potential of Lebrikizumab in the Treatment of Atopic Dermatitis

[4] Emma Guttman-Yassky, et al. JAMA Dermatol. Efficacy and Safety of Lebrikizumab, a High-Affinity Interleukin 13 Inhibitor, in Adults With Moderate to Severe Atopic Dermatitis: A Phase 2b Randomized Clinical Trial

[5] Sabina Antonela Antoniu. Expert Opin Investig Drugs. Lebrikizumab for the treatment of asthma

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Keywords: Lebrikizumab, TNX-650 supplier, IL Receptor/Related, inhibitors, activators

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