About 30 results found for searched term "Uridine" (0.034 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3135 | Zebularine | DNA Methyltransferase |
| NSC309132; 4-Deoxyuridine | ||
| Zebularine is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM. | ||
| M3379 | Trifluridine | DNA/RNA Synthesis |
| Trifluridine; FTD; 5-Trifluorothymidine; NSC 529182; NSC 75520 | ||
| Trifluridine (Trifluorothymidine) is an irreversible and orally active thymidylate synthase inhibitor, and thereby suppressing DNA synthesis. Trifluridine is an antiviral molecule used for research of HSV, rhabdovirus and orthopoxvirus infection. | ||
| M3816 | Uridine triphosphate trisodium | Others |
| UTP Trisodium Salt; Uridine 5'-triphosphate | ||
| Uridine triphosphate trisodium (UTP;Uridine 5'-triphosphate) is a nucleotide. | ||
| M4302 | Solasodine | p53 |
| Purapuridine; Solancarpidine; Solasodin | ||
| Solasodine (Purapuridine) is a steroid alkaloid found in solanaceae plants. Solasodine has neuroprotective, antifungal, antihypertensive, anticancer, antiatherosclerotic, antiandrogen and anti-inflammatory activities. | ||
| M4848 | 2'-deoxy-2'-Fluorouridine | Anti-infection |
| 2' -deoxy-2 '-fluorouridine can be used as an intermediate in the synthesis of reagents against antiinfluenza virus. | ||
| M5595 | Doxifluridine | Others |
| Ro 21-9738; 5-Fluoro-5'-deoxyuridine; 5'-DFUR | ||
| Doxifluridine(Ro 21-9738; 5'-DFUR) is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM. | ||
| M5648 | Floxuridine | DNA/RNA Synthesis |
| Deoxyfluorouridine; FUDR; NSC 27640 | ||
| Floxuridine (5-fluorouracil 2'-deoxyriboside) is a pyrimidine analogue that is also an antitumor metabolite of oncology. Floxuridine inhibits the Poly(ADP-Ribose) polymerase and induces DNA damage in vitro by activating ATM and ATR checkpoint signaling pathways. Floxuridine is an effective inhibitor of Staphylococcus aureus infection and can induce apoptosis. Floxuridine is resistant to HSV and CMV viruses. | ||
| M6046 | Uridine | DNA/RNA Synthesis |
| NSC 20256 | ||
| Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond. | ||
| M6348 | 5-BrdU | DNA/RNA Synthesis |
| BUdR; BRDU; Bromodeoxyuridine | ||
| 5-BrdU (Bromodeoxyuridine) is a synthetic thymidine analog; used for cell proliferation assays. | ||
| M8400 | Fialuridine | DNA/RNA Synthesis |
| FIAU; DRG-0098 | ||
| Fluuridine is a nucleoside antiviral compound. The compound showed significant mitochondrial toxicity. Fialuridine is also a DNA-directed DNA polymerase inhibitor that may be used to treat HBV infection and has potent activity against hepatitis B virus in vivo and in vitro. FIAU blocks DNA synthesis of human cytomegalovirus, hepatitis B and herpes simplex viruses. | ||
| M9020 | TAS-102 | DNA/RNA Synthesis |
| Trifluridine/Tipiracil HCl; Trifluridine-tipiracil hydrochloride mixture | ||
| TAS-102 is an orally administered combination of a thymidine-based nucleic acid analogue, trifluridine, and a thymidine phosphorylase inhibitor, tipiracil hydrochloride. | ||
| M9387 | Spermine | p53 |
| Neuridine | ||
| Spermine is a biogenic polyamine formed from spermidine, which binds to and activates NMDA and has been shown to potentiate NMDA-induced currents in a concentration-dependent manner. | ||
| M9791 | 5-Ethynyl-2'-deoxyuridine | PROTAC Linker |
| Edu | ||
| 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. | ||
| M10064 | Uridine 5'-diphosphoglucose disodium salt | P2 Receptor |
| UDP-Glc | ||
| Uridine 5'-diphosphoglucose disodium salt is an agonist of the P2Y14 receptor, with EC50 of 0.35 μM. Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM. | ||
| M10188 | 2,2'-Cyclouridine | Reverse Transcriptase |
| 2,2'-Anhydrouridine | ||
| 2,2'-Cyclouridine is a research tool for antiviral and anticancer studies. | ||
| M10804 | cedazuridine | Others |
| Cedazuridine has antineoplastic property. | ||
| M14350 | 5,6-Dihydrouridine | Metabolite/Endogenous Metabolite |
| 5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Bacteria, Eukaryota, and some Archaea. | ||
| M14355 | 5-Methyluridine | Metabolite/Endogenous Metabolite |
| 5-Methyluridine is a is an endogenous methylated nucleoside found in human fluids. | ||
| M14416 | Uridine triphosphate | Metabolite/Endogenous Metabolite |
| UTP; Uridine 5'-triphosphate | ||
| Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states. | ||
| M21143 | 5-Fluorouridine | DNA/RNA Synthesis |
| 5-Fluorouridine is a metabolite of 5-fluorouracil, a potent inhibitor of nuclease autocleavage. 5-Fluorouridine binds to total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis (cell death). | ||
| M20497 | 2’-deoxyuridine | Others |
| 2'-Deoxyuridine is an inhibitor of HSV-1 pyrimidine deoxythymidine kinase using 2-[14C]deoxythymidine as substrate. | ||
| M20756 | 2'-Deoxyuridine 5'-monophosphate disodium salt | Others |
| dUMP | ||
| 2'-Deoxyuridine 5'-monophosphate disodium salt (dUMP) is a substrate for thymidylate synthase and is converted to deoxythymidine monophosphate (dTMP). The inhibition of dUMP to dTMP at the methylation step is a key in controlling bacterial and eukaryotic cell growth. | ||
| M20962 | Uridine triacetate | Others |
| Vistonuridine, PN401; TAU | ||
| Uridine triacetate is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity. | ||
| M21596 | Pseudouridine | Metabolite/Endogenous Metabolite |
| Pseudouridine, an isomer of uridine, is also the most abundant modified nucleoside in non-coding RNA. Pseudouridine can fine-tune and stabilize the regional structure in rRNA and tRNA to maintain their function in mRNA decoding, ribosome assembly, processing, and translation. | ||
| M22158 | Deoxypseudouridine | Others |
| Deoxypseudouridine | ||
| M22374 | Fosifloxuridine nafalbenamide | Others |
| NUC-3373 | ||
| Fosifloxuridine nafalbenamide | ||
| M30498 | 5-Ethynyluridine | Others |
| 5-EU | ||
| 5-Ethynyluridine (5-EU) is a potent cell-permeable nucleoside can be used to label newly synthesized RNA. 5-Ethynyluridine can be used for isolation and sequencing of nascent RNA from neuronal populations in vivo. 5-Ethynyluridine can be used to identify changes in transcription in vivo in nervous system disease models. | ||
| M31258 | 5-Chloro-2'-deoxyuridine | Others |
| 5-Chloro-2'-deoxyuridine, a thymine analog, is to study the potential of hypochlorous acid damage to DNA and DNA precursors. | ||
| M31294 | Uridine 5'-monophosphate | Metabolite/Endogenous Metabolite |
| 5'-Uridylic acid; UMP | ||
| Uridine 5'-monophosphate is a ribonucleotide that can be formed by decarboxylation of whey acid nucleoside-5 '-monophosphate (5'-OMP) by OMP decarboxylase and is the major nucleotide analog in mammalian milk. | ||
| M39968 | 2′-O-Methyluridine | Others |
| 2'-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota. | ||
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