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2'-Deoxyuridine 5'-monophosphate disodium salt

Cat. No. M20756

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2'-Deoxyuridine 5'-monophosphate disodium salt Structure
Synonym:

dUMP

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Quality Control & Documentation
Biological Activity

2'-Deoxyuridine 5'-monophosphate disodium salt (dUMP) is a substrate for thymidylate synthase and is converted to deoxythymidine monophosphate (dTMP). The inhibition of dUMP to dTMP at the methylation step is a key in controlling bacterial and eukaryotic cell growth.

Chemical Information
Molecular Weight 352.15
Formula C9H11N2Na2O8P
CAS Number 42155-08-8
Solubility (25°C) DMSO 20 mg/mL
Water 70 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ryan S Funk, et al. J Pharmacol Exp Ther. Low-dose methotrexate results in the selective accumulation of aminoimidazole carboxamide ribotide in an erythroblastoid cell line

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Keywords: 2'-Deoxyuridine 5'-monophosphate disodium salt, dUMP supplier, inhibitors, activators

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