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Pseudouridine

Cat. No. M21596

All AbMole products are for research use only, cannot be used for human consumption.

Pseudouridine Structure
Size Price Availability Quantity
5mg USD 35  USD35 In stock
10mg USD 55  USD55 In stock
25mg USD 105  USD105 In stock
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Quality Control & Documentation
Biological Activity

Pseudouridine, an isomer of uridine, is also the most abundant modified nucleoside in non-coding RNA. Pseudouridine can fine-tune and stabilize the regional structure in rRNA and tRNA to maintain their function in mRNA decoding, ribosome assembly, processing, and translation.

Chemical Information
Molecular Weight 244.20
Formula C9H12N2O6
CAS Number 1445-07-4
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chen Xue, et al. Signal Transduct Target Ther. Role of main RNA modifications in cancer: N6-methyladenosine, 5-methylcytosine, and pseudouridine

[2] Jonas Cerneckis, et al. Trends Pharmacol Sci. Decoding pseudouridine: an emerging target for therapeutic development

[3] Jennifer A Stockert, et al. Urol Oncol. Pseudouridine as a novel biomarker in prostate cancer

[4] Thomas M Carlile, et al. Nature. Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

[5] Katalin Karik, et al. Mol Ther. Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability

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